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美国女性全膝关节置换术前和术后身体功能的种族/民族差异。

Racial/Ethnic Disparities in Physical Function Before and After Total Knee Arthroplasty Among Women in the United States.

机构信息

Joint Doctoral Program in Public Health, San Diego State University/University of California, San Diego, San Diego.

Doctor of Physical Therapy Program, San Diego State University, San Diego, California.

出版信息

JAMA Netw Open. 2020 May 1;3(5):e204937. doi: 10.1001/jamanetworkopen.2020.4937.

Abstract

IMPORTANCE

Although racial/ethnic differences in functional outcomes after total knee arthroplasty (TKA) exist, whether such differences are associated with differences in presurgical physical function (PF) has not been thoroughly investigated.

OBJECTIVE

To examine trajectories of PF by race/ethnicity before and after TKA among older women.

DESIGN, SETTING, AND PARTICIPANTS: This cohort study was conducted among the prospective Women's Health Initiative with linked Medicare claims data. A total of 10 325 community-dwelling women throughout the United States with Medicare fee-for-service underwent primary TKA between October 1, 1993, and December 31, 2014, and were followed up through March 31, 2017.

EXPOSURES

Race/ethnicity comparisons between Hispanic or Latina women, non-Hispanic black or African American women, and non-Hispanic white women (hereafter referred to as Hispanic, black, and white women, respectively).

MAIN OUTCOMES AND MEASURES

Physical functioning scale scores and self-reported activity limitations with walking 1 block, walking several blocks, and climbing 1 flight of stairs were measured by the RAND 36-Item Health Survey during the decade before and after TKA, with a median of 9 PF measurements collected per participant over time.

RESULTS

In total, 9528 white women (mean [SD] age at surgery, 74.6 [5.5] years), 622 black women (mean [SD] age at surgery, 73.1 [5.3] years), and 175 Hispanic women (mean [SD] age at surgery, 73.1 [5.2] years) underwent TKA. During the decade prior to TKA, black women had lower PF scores than white women (mean difference, -5.8 [95% CI, -8.0 to -3.6]) and higher odds of experiencing difficulty walking a single block (5 years before TKA: odds ratio, 1.86 [95% CI, 1.57-2.21]), walking multiple blocks (odds ratio, 2.14 [95% CI, 1.83-2.50]), and climbing 1 flight of stairs (odds ratio, 1.81 [95% CI, 1.55-2.12]). After TKA, black women continued to have lower PF scores throughout the decade (mean difference 1 year after TKA, -7.8 [95% CI, -10.8 to -4.9]). After adjusting for preoperative PF scores, PF scores after TKA were attenuated (mean difference 1 year after TKA, -3.0 [95% CI, -5.3 to -0.7]), with no statistically significant differences in long-term follow-up. Hispanic women had similar PF scores to white women during the pre-TKA and post-TKA periods.

CONCLUSIONS AND RELEVANCE

This study suggests that black women had significantly poorer PF than white women during the decades before and after TKA. Poorer PF after surgery was associated with poorer preoperative PF. Reducing disparities in post-TKA functional outcomes should target maintenance of function preoperatively in the early stages of arthritic disease and/or reduction of delays to receiving TKA once need arises.

摘要

重要性

尽管全膝关节置换术(TKA)后存在功能结果的种族/民族差异,但这些差异是否与术前身体功能(PF)的差异有关尚未得到彻底研究。

目的

在老年女性中,检查 TKA 前后 PF 的轨迹。

设计、地点和参与者:这项队列研究是在美国妇女健康倡议中进行的,该倡议与医疗保险索赔数据相关联。在美国各地的 10325 名居住在社区的女性接受了 Medicare 付费的初次 TKA,时间为 1993 年 10 月 1 日至 2014 年 12 月 31 日,并通过 2017 年 3 月 31 日进行了随访。

暴露

西班牙裔或拉丁裔女性、非西班牙裔黑人和非西班牙裔白人之间的种族/民族比较(下文分别称为西班牙裔、黑人和白人女性)。

主要结果和测量

在 TKA 前十年和后十年期间,通过 RAND 36-Item 健康调查测量了身体功能量表评分和自我报告的步行 1 个街区、步行多个街区和爬 1 个楼梯的活动限制,每位参与者平均有 9 个 PF 测量值随时间收集。

结果

共有 9528 名白人女性(手术时平均[SD]年龄,74.6[5.5]岁)、622 名黑人女性(手术时平均[SD]年龄,73.1[5.3]岁)和 175 名西班牙裔女性(手术时平均[SD]年龄,73.1[5.2]岁)接受了 TKA。在 TKA 前十年期间,黑人女性的 PF 评分低于白人女性(平均差异,-5.8[95%CI,-8.0 至-3.6]),并且在单一街区行走困难的几率更高(5 年前 TKA:比值比,1.86[95%CI,1.57-2.21]),走多个街区(比值比,2.14[95%CI,1.83-2.50])和爬 1 个楼梯(比值比,1.81[95%CI,1.55-2.12])。TKA 后,黑人女性在整个十年中继续保持较低的 PF 评分(TKA 后 1 年的平均差异,-7.8[95%CI,-10.8 至-4.9])。在调整术前 PF 评分后,TKA 后 PF 评分减弱(TKA 后 1 年的平均差异,-3.0[95%CI,-5.3 至-0.7]),在长期随访中无统计学意义。西班牙裔女性在 TKA 前和 TKA 后期间的 PF 评分与白人女性相似。

结论和相关性

本研究表明,黑人女性在 TKA 前后几十年的 PF 明显差于白人女性。术后 PF 较差与术前 PF 较差有关。减少 TKA 后功能结果的差异应针对在关节炎疾病的早期阶段维持术前功能,或一旦需要,减少接受 TKA 的延迟。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c1/7229524/750405eeb4aa/jamanetwopen-3-e204937-g001.jpg

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