Department of Orthopaedic Surgery and Duke Clinical Research Institute, Duke University; Durham, North Carolina.
Department of Orthopaedic Surgery, Division of Adult Reconstruction, Duke University, Durham, North Carolina.
J Pain. 2022 Mar;23(3):450-458. doi: 10.1016/j.jpain.2021.09.007. Epub 2021 Oct 20.
Hip, knee, and shoulder arthroplasty are among the most frequently performed orthopaedic procedures in the United States. High impact and bothersome chronic pain rates following total joint arthroplasty (TJA) are unknown; as are factors that predict these chronic pain outcomes. This retrospective observational study included individuals that had a TJA from January 2014 to January 2020 (n = 2,638). Pre-operative and clinical encounter information was extracted from the electronic health record and chronic pain state was determined by email survey. Predictor variables included TJA location, number of surgeries, comorbidities, tobacco use, BMI, and pre-operative pain intensity. Primary outcomes were high impact and bothersome chronic pain. Rates of high impact pain (95% CI) were comparable for knee (9.8-13.3%), hip (8.3-11.8%) and shoulder (7.6-16.3%). Increased risk of high impact pain included non-white race, two or more comorbidities, age less than 65 years, pre-operative pain scores 5/10 or higher, knee arthroplasty, and post-operative survey completion 24 months or less. Rates of bothersome chronic pain (95% CI) were also comparable for knee (24.9-29.9%) and hip (21.3-26.3%) arthroplasty; but higher for shoulder (26.9-39.6%). Increased risk of bothersome chronic pain included non-white race, shoulder arthroplasty, knee arthroplasty, current or past tobacco use, and being female. PERSPECTIVE: In this cohort more than 1/3rd of individuals reported high impact or bothersome chronic pain following TJA. Non-white race and knee arthroplasty were the only two variables associated with both chronic pain outcomes.
髋关节、膝关节和肩关节置换术是美国最常进行的矫形手术之一。全关节置换术后(TJA)的高影响和令人困扰的慢性疼痛发生率尚不清楚;预测这些慢性疼痛结果的因素也尚不清楚。本回顾性观察研究纳入了 2014 年 1 月至 2020 年 1 月期间接受 TJA 的个体(n=2638)。从电子健康记录中提取术前和临床就诊信息,并通过电子邮件调查确定慢性疼痛状态。预测变量包括 TJA 部位、手术次数、合并症、吸烟状况、BMI 和术前疼痛强度。主要结局为高影响和令人困扰的慢性疼痛。膝关节(95%CI:9.8-13.3%)、髋关节(95%CI:8.3-11.8%)和肩关节(95%CI:7.6-16.3%)的高影响疼痛发生率相当。高影响疼痛风险增加的因素包括非白种人、两种或两种以上合并症、年龄小于 65 岁、术前疼痛评分 5/10 或更高、膝关节置换术和术后 24 个月内完成调查。膝关节(95%CI:24.9-29.9%)和髋关节(95%CI:21.3-26.3%)置换术后的慢性疼痛发生率也相当;但肩关节置换术后(95%CI:26.9-39.6%)更高。高影响慢性疼痛的风险因素包括非白种人、肩关节置换术、膝关节置换术、当前或过去吸烟以及女性。观点:在本队列中,超过 1/3 的个体在 TJA 后报告有高影响或令人困扰的慢性疼痛。非白种人和膝关节置换术是唯一与两种慢性疼痛结果相关的两个变量。