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非圆形角膜移植技术。

Techniques of noncircular corneal transplantation.

机构信息

Division of Ophthalmology and Visual Sciences, Eye ENT Centre, Queens Medical Centre, University of Nottingham, UK.

Royal Victorian Eye and Ear Hospital.

出版信息

Curr Opin Ophthalmol. 2020 Jul;31(4):293-301. doi: 10.1097/ICU.0000000000000672.

Abstract

PURPOSE OF REVIEW

The management of peripheral corneal diseases, including Mooren's ulcer, Terrien's marginal degeneration, peripheral ulcerative keratitis and pellucid marginal degeneration is challenging. Circular grafts must either be very large, resulting in the excision of healthy tissue, or eccentric, leading to high levels of astigmatism. This review summarizes the range of noncircular keratoplasty procedures available to surgeons, in addition to their indications, and surgical techniques.

RECENT FINDINGS

Noncircular grafts have been demonstrated to be useful in the management of peripheral corneal diseases. They are effective at providing tectonic support and also facilitate visual rehabilitation. Specifically, they produce favourable postoperative visual and astigmatic outcomes. The evidence relating to these procedures is largely limited to case reports and case series, with no large-scale studies available.

SUMMARY

Noncircular keratoplasty procedures are useful in the management of peripheral corneal diseases, which is typically difficult. There is a need for larger studies to investigate the relative advantages and disadvantages of these procedures and further characterize their outcomes.

摘要

目的综述

周边角膜疾病(包括蚕蚀性角膜溃疡、边缘性角膜变性、周边溃疡性角膜病变和角膜边缘性营养不良)的治疗颇具挑战性。环形移植物要么非常大,导致健康组织被切除,要么偏心,导致高度散光。本文除了介绍适应证和手术技术外,还综述了外科医生可采用的各种非环形角膜移植术。

最新发现

非环形移植物已被证明可有效治疗周边角膜疾病。它们不仅可提供结构支持,还有助于视力康复。具体来说,它们可带来良好的术后视力和散光结果。这些手术的证据主要限于病例报告和病例系列,尚无大规模研究。

总结

非环形角膜移植术对治疗通常较为棘手的周边角膜疾病很有用。需要进行更大规模的研究,以调查这些手术的相对优势和劣势,并进一步明确其结果。

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