• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

肉毒毒素治疗露龈笑的疗效。

Efficacy of botulinum toxin for treating a gummy smile.

机构信息

Private Practice, Mersin, Turkey.

Department of Orthodontics, Faculty of Dentistry, Gaziantep University, Gaziantep, Turkey.

出版信息

Am J Orthod Dentofacial Orthop. 2020 Jul;158(1):50-58. doi: 10.1016/j.ajodo.2019.07.014. Epub 2020 May 12.

DOI:10.1016/j.ajodo.2019.07.014
PMID:32414547
Abstract

INTRODUCTION

This study was conducted to investigate the efficacy of botulinum toxin applied to the different muscles of patients who have excessive gingival display and to evaluate the return to baseline gingival exposure value.

METHODS

Twenty-eight patients who had a gummy smile of more than 2 mm were randomly divided into 2 groups. Botulinum toxin was administered equally to the left and right of the levator labii superioris alaeque nasi muscle of group 1 and the orbicularis oris site of group 2. Photographs were taken, and measurements were taken before injection and at 3 days, 15 days, 1 month, 4 months, 5 months, and 6 months after injection. The visual analogue scale was used to assess the level of satisfaction.

RESULTS

The average amount of visible gingiva in group 1 was 4.92 mm at the beginning of the treatment and 1.92 mm on the 15th day. In group 2, the average amount of visible gingiva was 4.58 mm at the beginning of treatment and 2.16 mm on the 15th day. In both treatment groups, it was determined that the measurements on the sixth month did not return to their initial values. The decrease in gingival appearances in group 1 was greater than in group 2. There was no significant difference between the groups in terms of return to baseline gingival exposure value. In both groups, it was seen that the increase in satisfaction in patients was high.

CONCLUSIONS

For gummy smile correction, botulinum toxin injection is thought to be an alternative method because it is effective and conservative and has high patient satisfaction.

摘要

简介

本研究旨在探究在存在过度牙龈显露的患者的不同肌肉中应用肉毒毒素的疗效,并评估牙龈显露值恢复至基线的情况。

方法

将 28 名牙龈显露超过 2mm 的露龈笑患者随机分为两组。第 1 组等量注射至提上唇鼻翼肌的左侧和右侧,第 2 组等量注射至口轮匝肌。在注射前、注射后 3 天、15 天、1 个月、4 个月、5 个月和 6 个月拍摄照片并进行测量。采用视觉模拟评分评估满意度。

结果

治疗开始时,第 1 组的平均可见牙龈量为 4.92mm,第 15 天为 1.92mm。第 2 组治疗开始时的平均可见牙龈量为 4.58mm,第 15 天为 2.16mm。在两组治疗中,第 6 个月的测量值均未恢复至初始值。第 1 组的牙龈外观减少量大于第 2 组。两组间牙龈显露值恢复至基线的情况无显著差异。两组患者的满意度均增高。

结论

对于露龈笑的矫正,肉毒毒素注射被认为是一种有效的替代方法,因为它具有有效性和保守性,并且患者满意度高。

相似文献

1
Efficacy of botulinum toxin for treating a gummy smile.肉毒毒素治疗露龈笑的疗效。
Am J Orthod Dentofacial Orthop. 2020 Jul;158(1):50-58. doi: 10.1016/j.ajodo.2019.07.014. Epub 2020 May 12.
2
Application of Botulinum Toxin at the Yonsei Point for the Treatment of Gummy Smile: A Randomized Controlled Trial.肉毒毒素在延世点治疗露龈笑的应用:一项随机对照试验。
Plast Reconstr Surg. 2024 Apr 1;153(4):711e-721e. doi: 10.1097/PRS.0000000000010623. Epub 2023 May 2.
3
OnabotulinumtoxinA for the treatment of a "gummy smile".A型肉毒毒素用于治疗“露龈笑”。
Aesthet Surg J. 2014 Mar;34(3):432-7. doi: 10.1177/1090820X14527603.
4
Botulinum toxin type A for the treatment of excessive gingival display - A systematic review.A型肉毒毒素治疗牙龈过度暴露 - 系统评价。
J Stomatol Oral Maxillofac Surg. 2022 Nov;123(6):e717-e723. doi: 10.1016/j.jormas.2022.05.016. Epub 2022 May 14.
5
A simplified method for smile enhancement: botulinum toxin injection for gummy smile.一种简单的微笑增强方法:肉毒毒素注射治疗露龈笑。
Plast Reconstr Surg. 2012 Sep;130(3):726-728. doi: 10.1097/PRS.0b013e31825dc32f.
6
Dose and injection site of botulinum toxin type A for gummy smile management: A systematic review and bibliometric analysis.A型肉毒毒素用于管理 Gummy Smile 的剂量和注射部位:系统评价和文献计量分析。
Toxicon. 2024 Oct;249:108058. doi: 10.1016/j.toxicon.2024.108058. Epub 2024 Aug 10.
7
Botulinum Toxin A in the Management of a Gummy Smile: A Clinical Controlled Preliminary Study.A型肉毒毒素治疗露龈笑的临床对照初步研究。
Aesthet Surg J. 2022 Mar 15;42(4):421-430. doi: 10.1093/asj/sjab342.
8
Therapeutic effects of botulinum toxin type A in subjects with gummy smile: A longitudinal sEMG approach.A型肉毒毒素治疗露龈笑的疗效:纵向表面肌电图研究。
Int Orthod. 2021 Dec;19(4):652-658. doi: 10.1016/j.ortho.2021.07.004. Epub 2021 Sep 17.
9
Botulinum Toxin Type-A for the Treatment of Excessive Gingival Display on Smiling.A型肉毒杆菌毒素治疗微笑时牙龈过度外露
J Contemp Dent Pract. 2020 Sep 1;21(9):1018-1021.
10
Botulinum toxin type A (Botox) for the neuromuscular correction of excessive gingival display on smiling (gummy smile).A型肉毒杆菌毒素(保妥适)用于微笑时牙龈过度外露(露龈笑)的神经肌肉矫正。
Am J Orthod Dentofacial Orthop. 2008 Feb;133(2):195-203. doi: 10.1016/j.ajodo.2007.04.033.

引用本文的文献

1
Pink esthetic treatment of gingival recession, black triangle, and gummy smile: a narrative review.牙龈退缩、黑三角和牙龈微笑的粉色美学治疗:一项叙述性综述。
Maxillofac Plast Reconstr Surg. 2025 Jul 17;47(1):17. doi: 10.1186/s40902-025-00467-8.
2
Impact of fixed orthodontic treatment with and without premolar extraction on gingival display index in men and women.固定正畸治疗(有无拔除前磨牙)对男性和女性牙龈暴露指数的影响。
Sci Rep. 2025 Jul 5;15(1):24017. doi: 10.1038/s41598-025-10233-5.
3
The Comparative Study of the Effects of Botulinum Toxin Micro-droplet Injection Combined with Micro-crosslinked Sodium Hyaluronate Gel or Focused Ultrasound Technology in Facial Rejuvenation Treatment.
肉毒杆菌毒素微滴注射联合微交联透明质酸钠凝胶或聚焦超声技术对面部年轻化治疗效果的比较研究
Aesthetic Plast Surg. 2025 Jun 4. doi: 10.1007/s00266-025-04903-y.
4
Botulinum Toxin Type A and Hyaluronic Acid Dermal Fillers in Dentistry: A Systematic Review of Clinical Application and Indications.A型肉毒杆菌毒素和透明质酸真皮填充剂在牙科中的应用:临床应用和适应症的系统评价
J Clin Med Res. 2024 Jun;16(6):273-283. doi: 10.14740/jocmr5202. Epub 2024 Jun 30.
5
A Systematic Review and Meta-Analysis Comparing Surgical and Nonsurgical Treatments for Excessive Gingival Display.一项比较手术和非手术治疗牙龈过度外露的系统评价与荟萃分析。
Dent J (Basel). 2024 May 22;12(6):154. doi: 10.3390/dj12060154.
6
Non-Surgical Management of the Gingival Smile with Botulinum Toxin A-A Systematic Review and Meta-Analysis.A型肉毒杆菌毒素非手术治疗龈笑的系统评价与荟萃分析
J Clin Med. 2023 Feb 10;12(4):1433. doi: 10.3390/jcm12041433.
7
An Approach for Gummy Smile Treatment Using Botulinum Toxin A: A Narrative Review of the Literature.使用A型肉毒杆菌毒素治疗露龈笑的方法:文献综述
Cureus. 2023 Jan 21;15(1):e34032. doi: 10.7759/cureus.34032. eCollection 2023 Jan.
8
Effect and longevity of botulinum toxin in the treatment of gummy smile: a meta-analysis and meta-regression.肉毒杆菌毒素治疗露龈笑的效果及持久性:一项荟萃分析和元回归分析
Clin Oral Investig. 2022 Jan;26(1):109-117. doi: 10.1007/s00784-021-04223-w. Epub 2021 Oct 15.
9
Gummy Smile Management Using Diode Laser Gingivectomy Versus Botulinum Toxin Injection - A Prospective Study.使用二极管激光牙龈切除术与肉毒杆菌毒素注射治疗露龈笑的前瞻性研究
Ann Maxillofac Surg. 2021 Jan-Jun;11(1):70-74. doi: 10.4103/ams.ams_458_20. Epub 2021 Jul 24.