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[近交系大鼠对A群链球菌多糖的免疫反应]

[Immune response of rats of inbred strains to the polysaccharide of group A streptococci].

作者信息

Krylov M Iu

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1977 Mar(3):82-6.

PMID:324197
Abstract

Immune response to polysaccharide of group A streptococcus was studied in rats of inbred strains MCY, VAG and August. Pure antibodies to beta-N-acetylglucosamine were isolated; their chromatography (by affinity) was conducted, and the content of the molecules of the IgG and IgM classes was established in each antibody fraction. Interlinear differences were revealed by each of the signs under study, this pointing to the role of genetic factors in the formation of antibodies to polysaccharide of group A streptococcus.

摘要

在近交系MCY、VAG和奥古斯特大鼠中研究了对A组链球菌多糖的免疫反应。分离出了针对β-N-乙酰葡糖胺的纯抗体;对其进行了(亲和)色谱分析,并确定了每个抗体组分中IgG和IgM类分子的含量。在所研究的每个指标中都发现了品系间差异,这表明遗传因素在A组链球菌多糖抗体形成中起作用。

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