纳米技术在男科学中的发展。
Development of nanotechnology in andrology.
作者信息
Liu Sheng-Zhuo, Feng De-Chao, Liu Zhi-Hong, Liang Jia-Yu, Ren Zheng-Ju, Zhou Chuan, Wu Kan, Zhang Fu-Xun, Zhang Fan, Lu Yi-Ping, Wang Xian-Ding
机构信息
Department of Urology/Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
出版信息
Transl Androl Urol. 2020 Apr;9(2):702-708. doi: 10.21037/tau.2020.01.18.
Abstract
Since first introduced in 1980s, nanotechnology has always been the eye-catching point as its providing us with new approaches to explore the microscopic world. Many nanotechnology-associated novel technologies have been brought into clinical use in the past decades and uncountable patients benefited from them, which convinces us of a bright prospect of nanotechnology in the field of medicine. In this review, literatures concerning nanotechnology applications in andrology were retrieved and we made a comprehensive discussion on drug delivery, gene therapy and stem cell therapy use in andrology, which calls for the engagement of nanotechnology.
摘要
自20世纪80年代首次引入以来，纳米技术一直备受关注，因为它为我们探索微观世界提供了新方法。在过去几十年中，许多与纳米技术相关的新技术已应用于临床，无数患者从中受益，这让我们相信纳米技术在医学领域有着光明的前景。在这篇综述中，我们检索了有关纳米技术在男科学中应用的文献，并对男科学中药物递送、基因治疗和干细胞治疗中纳米技术的应用进行了全面讨论。
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2
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Curr Urol Rep. 2019 Jun 18;20(8):44. doi: 10.1007/s11934-019-0908-2.
3
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