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Intranasal Tadalafil nanoemulsions: formulation, characterization and pharmacodynamic evaluation.鼻腔给予他达拉非纳米乳剂:制剂、特性描述和药效学评价。
Pharm Dev Technol. 2019 Nov;24(9):1083-1094. doi: 10.1080/10837450.2019.1631846. Epub 2019 Jul 29.
2
Emerging Treatments for Erectile Dysfunction: a Review of Novel, Non-surgical Options.勃起功能障碍的新兴治疗方法:新型非手术选择综述
Curr Urol Rep. 2019 Jun 18;20(8):44. doi: 10.1007/s11934-019-0908-2.
3
Virus-like nanoparticles as a novel delivery tool in gene therapy.病毒样纳米颗粒作为基因治疗的新型递送工具。
Biochimie. 2019 Feb;157:38-47. doi: 10.1016/j.biochi.2018.11.001. Epub 2018 Nov 5.
4
Advances in Gene Therapy for Erectile Dysfunction: Promises and Challenges.基因治疗勃起功能障碍的进展:前景与挑战。
Curr Gene Ther. 2018;18(6):351-365. doi: 10.2174/1566523218666181004145424.
5
Stem cell therapy in erectile dysfunction: science fiction or realistic treatment option?干细胞疗法治疗勃起功能障碍:科幻还是现实治疗选择?
Hormones (Athens). 2018 Sep;17(3):315-320. doi: 10.1007/s42000-018-0050-4. Epub 2018 Aug 21.
6
A treatment algorithm for healthy young men with erectile dysfunction.健康年轻男性勃起功能障碍的治疗算法。
BJU Int. 2019 Jan;123(1):173-179. doi: 10.1111/bju.14458. Epub 2018 Aug 28.
7
Comparative study of transdermal drug delivery systems of resveratrol: High efficiency of deformable liposomes.白藜芦醇经皮给药系统的比较研究:变形脂质体的高效性。
Mater Sci Eng C Mater Biol Appl. 2018 Sep 1;90:356-364. doi: 10.1016/j.msec.2018.04.073. Epub 2018 Apr 28.
8
Low dose daily versus on-demand high dose tadalafil in diabetic patients with erectile and ejaculatory dysfunction.糖尿病性勃起和射精功能障碍患者每日低剂量与按需高剂量他达拉非的比较。
Int J Impot Res. 2018 Jun;30(3):102-107. doi: 10.1038/s41443-018-0019-5. Epub 2018 May 25.
9
Novel instantly-dispersible nanocarrier powder system (IDNPs) for intranasal delivery of dapoxetine hydrochloride: in-vitro optimization, ex-vivo permeation studies, and in-vivo evaluation.用于盐酸达泊西汀鼻内递送的新型即刻分散纳米载体粉末系统(IDNPs):体外优化、体外渗透研究和体内评价。
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Adipose-Derived Stem Cell-Derived Exosomes Ameliorate Erectile Dysfunction in a Rat Model of Type 2 Diabetes.脂肪来源干细胞衍生的外泌体改善2型糖尿病大鼠模型的勃起功能障碍
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纳米技术在男科学中的发展。

Development of nanotechnology in andrology.

作者信息

Liu Sheng-Zhuo, Feng De-Chao, Liu Zhi-Hong, Liang Jia-Yu, Ren Zheng-Ju, Zhou Chuan, Wu Kan, Zhang Fu-Xun, Zhang Fan, Lu Yi-Ping, Wang Xian-Ding

机构信息

Department of Urology/Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.

出版信息

Transl Androl Urol. 2020 Apr;9(2):702-708. doi: 10.21037/tau.2020.01.18.

DOI:10.21037/tau.2020.01.18
PMID:32420177
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7214986/
Abstract

Since first introduced in 1980s, nanotechnology has always been the eye-catching point as its providing us with new approaches to explore the microscopic world. Many nanotechnology-associated novel technologies have been brought into clinical use in the past decades and uncountable patients benefited from them, which convinces us of a bright prospect of nanotechnology in the field of medicine. In this review, literatures concerning nanotechnology applications in andrology were retrieved and we made a comprehensive discussion on drug delivery, gene therapy and stem cell therapy use in andrology, which calls for the engagement of nanotechnology.

摘要

自20世纪80年代首次引入以来,纳米技术一直备受关注,因为它为我们探索微观世界提供了新方法。在过去几十年中,许多与纳米技术相关的新技术已应用于临床,无数患者从中受益,这让我们相信纳米技术在医学领域有着光明的前景。在这篇综述中,我们检索了有关纳米技术在男科学中应用的文献,并对男科学中药物递送、基因治疗和干细胞治疗中纳米技术的应用进行了全面讨论。