Xu Qian, Luan Jie
School of Medicine, Southeast University, Nanjing 210009, Jiangsu Province, China.
Department of Ophthalmology, Zhongda Hospital, Southeast University, Nanjing 210009, Jiangsu Province, China.
Int J Ophthalmol. 2020 May 18;13(5):822-831. doi: 10.18240/ijo.2020.05.19. eCollection 2020.
Vitrectomy combined with internal limiting membrane (ILM) peeling is popular for the treatment of macular hole (MH). However, the improvements of MH closure rate and postoperative visual acuity are not satisfactory especially in large and refractory MHs. Currently, the ILM flap technique has gradually been applied for the treatment of MH and achieved high MH closure rate. The ILM flap technique has many variations, including the difference of the size, shape, number, and manner in which the flaps put on the MHs. The ILM flap technique also has some auxiliary means including perfluoro-n-octane (PFO), dye, autologous blood and adhesive viscoelastics. There is controversy about the effects between several technique variations of ILM flap, and it needs to be explored in the future.
玻璃体切除术联合内界膜(ILM)剥除术在黄斑裂孔(MH)治疗中应用广泛。然而,尤其是在巨大和难治性黄斑裂孔中,黄斑裂孔闭合率及术后视力的改善并不理想。目前,内界膜瓣技术已逐渐应用于黄斑裂孔治疗并取得了较高的黄斑裂孔闭合率。内界膜瓣技术有多种变化形式,包括瓣的大小、形状、数量以及覆盖黄斑裂孔的方式等方面的差异。内界膜瓣技术还有一些辅助手段,包括全氟正辛烷(PFO)、染料、自体血和黏弹剂。关于内界膜瓣的几种技术变化形式之间的效果存在争议,未来仍需进一步探索。