Clinical Department of Neurosurgery, Central Clinical Hospital of the Ministry of the Interior and Administration in Warsaw, Warsaw, Poland
Center for Postgraduate Medical Education, Warsaw, Poland; Clinical Department of Interventional Cardiology, Central Clinical Hospital of the Ministry of the Interior and Administration in Warsaw, Warsaw, Poland.
Pol Arch Intern Med. 2020 May 29;130(5):407-411. doi: 10.20452/pamw.15361. Epub 2020 May 18.
Since the first reported case of coronavirus disease 2019 (COVID‑19) in Poland, the worldwide pandemic has spread throughout the country, leading to many hospital admissions. There has been an urgent need to determine clinical characteristics of Polish patients with laboratory‑confirmed severe acute respiratory syndrome coronavirus 2 (SARS‑CoV 2) infection in the clinical setting.
The aim of this retrospective study was to outline characteristics and short‑ term outcomes of SARS‑CoV‑2-positive patients.
We retrospectively assessed 169 consecutive patients with laboratory‑ confirmed COVID‑ 19 with regard to their clinical manifestations, radiological findings, treatment, complications, and outcomes.
Of the 169 patients, more than half was aged 65 years or older (88; 52.1%), 51.5% were male, and 78.3% had comorbidities. The majority of patients (106; 62.7%) were transferred from outbreak locations in medical facilities. The most common symptoms on admission were fever (42%), shortness of breath (35%), and fatigue (33%). Twenty seven (15.4%) patients required intensive care unit admission. Overall mortality was 26.3% (n = 46) and was significantly higher in patients transferred from other facilities (38 out of 106; 35.8%), than in patients admitted directly to the hospital (8 out of 63; 12.69%; P <0.001). Seventeen out of 29 patients admitted to the intensive care unit died (mortality, 58.6%), including 30 out of 41 patients with acute respiratory distress syndrome (73.2% mortality rate).
Polish patients with COVID‑19 have similar characteristics and risk factors for adverse outcomes to those observed in countries in which outbreaks occurred earlier. Significantly higher mortality in patients transferred from other centers warrants special attention and transfer policy should be verified.
自 2019 年冠状病毒病(COVID-19)在波兰首例报告以来,全球大流行已蔓延至全国各地,导致许多人住院。在临床环境中,迫切需要确定实验室确诊的严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)感染的波兰患者的临床特征。
本回顾性研究旨在概述 SARS-CoV-2 阳性患者的特征和短期结局。
我们回顾性评估了 169 例连续确诊的 COVID-19 患者的临床表现、影像学表现、治疗、并发症和结局。
在 169 例患者中,超过一半年龄在 65 岁或以上(88;52.1%),51.5%为男性,78.3%有合并症。大多数患者(106;62.7%)是从医疗机构的疫情地点转来的。入院时最常见的症状是发热(42%)、呼吸急促(35%)和乏力(33%)。27 例(15.4%)患者需要入住重症监护病房。总体死亡率为 26.3%(n=46),从其他医疗机构转来的患者死亡率明显更高(106 例中的 38 例,35.8%),而直接入院的患者死亡率较低(63 例中的 8 例,12.69%;P<0.001)。29 例入住重症监护病房的患者中有 17 例死亡(死亡率为 58.6%),其中包括 41 例急性呼吸窘迫综合征患者中的 30 例(死亡率为 73.2%)。
波兰 COVID-19 患者的特征和不良结局的危险因素与其他早期发生疫情的国家相似。从其他中心转来的患者死亡率明显更高,需要特别关注,应验证转院政策。