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神经外科手术模拟中脑肿瘤钝性分离的结缔组织损伤建模

Modeling of connective tissue damage for blunt dissection of brain tumor in neurosurgery simulation.

作者信息

Hou Wenguo, Liu Peter X, Zheng Minhua

机构信息

School of Mechanical, Electronic and Control Engineering, Beijing Jiaotong University, Beijing 100044, PR China.

Department of Systems and Computer Engineering, Carleton University, Ottawa, ON, Canada.

出版信息

Comput Biol Med. 2020 May;120:103696. doi: 10.1016/j.compbiomed.2020.103696. Epub 2020 Mar 6.

DOI:10.1016/j.compbiomed.2020.103696
PMID:32421640
Abstract

We introduce a new model for connective tissue damage in blunt dissection, which is a very important process in neurosurgery simulation. Specifically, the tool-tissue interaction between the instrument and connective tissue is incorporated into the model of connective tissue damage. This damage develops with the evolution criterion due to the effect of the external load. The tetrahedral mesh in the soft tissue model is removed for the representation of rupture as the damage accumulates to the threshold value. Analysis and experiments show that the connective tissue damage model provides stable, visually realistic results for the simulation of the connective tissue rupture process. The stiffness of the connective tissue decreases as the damage accumulates. The proposed model for connective tissue damage was incorporated into the development of a neurosurgery simulator, in which blunt dissection of a brain tumor was simulated.

摘要

我们引入了一种用于钝性分离中结缔组织损伤的新模型,钝性分离是神经外科模拟中一个非常重要的过程。具体而言,仪器与结缔组织之间的工具-组织相互作用被纳入结缔组织损伤模型。由于外部载荷的作用,这种损伤根据演化准则发展。随着损伤累积到阈值,软组织模型中的四面体网格被移除以表示破裂。分析和实验表明,结缔组织损伤模型为结缔组织破裂过程的模拟提供了稳定、视觉上逼真的结果。随着损伤的累积,结缔组织的刚度会降低。所提出的结缔组织损伤模型被纳入了一个神经外科模拟器的开发中,其中模拟了脑肿瘤的钝性分离。

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