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极年轻患者急性心肌梗死的流行病学特征和治疗模式:来自一家三级护理中心的研究。

Epidemiological profile and management patterns of acute myocardial infarction in very young patients from a tertiary care center.

机构信息

Department of Cardiology, G B Pant Institute of Post Graduate Medical Education and Research, New Delhi, India.

Department of Cardiology, G B Pant Institute of Post Graduate Medical Education and Research, New Delhi, India.

出版信息

Indian Heart J. 2020 Jan-Feb;72(1):32-39. doi: 10.1016/j.ihj.2020.03.003. Epub 2020 Mar 24.

Abstract

BACKGROUND

Cardiovascular disease is the leading cause of death in India. Previously it was thought to be a disease of the elderly but now an epidemiological transition is being seen with increasing incidence in the very young adults as well. Such patterns are not well studied in the South East Asian population.

OBJECTIVE

To study the epidemiological profile of very young (≤35 years) adults presenting with an acute myocardial infarction (AMI) in comparison with an older cohort.

METHODOLOGY

The present study included all patients presenting with AMI to the emergency or to the out-patient department of the G B Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi between January 2014 and October 2015. A total of 102 subjects ≤35 years with AMI comprised the study subjects (cases) and were compared with 104 subjects >35 years old with AMI (Controls).

RESULTS & CONCLUSION: Most of the very young AMI patients presented with an anterior wall ST segment elevation myocardial infarction, a stable hemodynamic profile, single vessel disease and better left ventricular ejection fraction as compared with controls. Most of the patients were from urban and semi-urban areas, middle and lower middle socioeconomic status and were smokers but lacked other traditional risk factors.

摘要

背景

心血管疾病是印度的主要死因。以前人们认为它是一种老年病,但现在随着年轻人中发病率的增加,也出现了一种流行病学转变。这种模式在东南亚人群中并没有得到很好的研究。

目的

与老年患者相比,研究急性心肌梗死(AMI)年轻(≤35 岁)患者的流行病学特征。

方法

本研究纳入了 2014 年 1 月至 2015 年 10 月期间在新德里的全印度医学科学研究所(GIPMER)急诊室或门诊就诊的所有 AMI 患者。共纳入 102 例年龄≤35 岁的 AMI 患者作为研究对象(病例组),并与 104 例年龄>35 岁的 AMI 患者(对照组)进行比较。

结果与结论

与对照组相比,大多数年轻的 AMI 患者表现为前壁 ST 段抬高型心肌梗死,血流动力学稳定,单支血管病变,左心室射血分数较好。大多数患者来自城市和半城市地区,中低社会经济地位,是吸烟者,但缺乏其他传统的危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/daf4/7231868/c3dde84ee451/gr1.jpg

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