Department of Nursing and Midwifery, University of the West of England Bristol, Bristol, Bristol, UK.
Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Ann Rheum Dis. 2020 Aug;79(8):1031-1036. doi: 10.1136/annrheumdis-2020-217301. Epub 2020 May 18.
In treat to target (T2T), the patient is treated to reach and maintain specified and sequentially measured goals, such as remission or low disease activity. T2T in psoriatic arthritis (PsA) has demonstrated improved clinical and patient-reported outcomes and is recommended in European guidelines. However, most clinicians do not use T2T in PsA. This study examined the barriers and enablers to implementation in practice.
Sequential mixed methods comprising a qualitative design (interviews and focus group) to inform a quantitative design (survey). Qualitative data were analysed thematically, and quantitative statistics were analysed descriptively.
Nineteen rheumatology clinicians participated in telephone interviews or a face-to-face focus group. An overarching theme 'Complexity' (including 'PsA vs Rheumatoid Arthritis', 'Measurement' and 'Resources') and an underpinning theme 'Changes to current practice' (including 'Reluctance due to organisational factors' and 'Individual determination to make changes') were identified. 153 rheumatology clinicians responded to an online survey. Barriers included limited clinical appointment time to collect outcome data (54.5%) and lack of training in assessing skin disease (35%). Enablers included provision of a protocol (86.4%), a local implementation lead (80.9%), support in clinic to measure outcomes (83.3%) and training in T2T (69.8%). The importance of regular audit with feedback, specialist PsA clinics and a web-based electronic database linked to hospital/national information technology (IT) systems were also identified as enablers.
Implementation of T2T in PsA requires an integrated approach to address the support, training and resource needs of individual clinicians, rheumatology teams, local IT systems and service providers to maximise success.
在针对目标(T2T)治疗中,患者接受治疗以达到并维持特定的、逐步测量的目标,如缓解或低疾病活动度。在银屑病关节炎(PsA)中,T2T 已显示出改善的临床和患者报告的结果,并被欧洲指南推荐。然而,大多数临床医生并没有在 PsA 中使用 T2T。本研究考察了在实践中实施的障碍和促进因素。
采用顺序混合方法,包括定性设计(访谈和焦点小组)为定量设计(调查)提供信息。对定性数据进行主题分析,对定量统计数据进行描述性分析。
19 名风湿病临床医生参加了电话访谈或面对面的焦点小组。一个总体主题 "复杂性"(包括 "PsA 与类风湿关节炎"、"测量" 和 "资源")和一个基础主题 "改变当前实践"(包括 "由于组织因素而不愿意" 和 "个人决心做出改变")被确定。153 名风湿病临床医生对在线调查做出了回应。障碍包括收集结果数据的临床预约时间有限(54.5%)和缺乏评估皮肤疾病的培训(35%)。促进因素包括提供方案(86.4%)、当地实施负责人(80.9%)、在诊所支持测量结果(83.3%)和 T2T 培训(69.8%)。定期进行有反馈的审计、专门的 PsA 诊所以及与医院/国家信息技术(IT)系统相关联的基于网络的电子数据库也被确定为促进因素。
在 PsA 中实施 T2T 需要采取综合方法,以满足个别临床医生、风湿病团队、当地 IT 系统和服务提供商的支持、培训和资源需求,以最大限度地提高成功率。