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冠状病毒的潜在神经影响:对新型 SARS-CoV-2 的启示。

Potential neurological impact of coronaviruses: implications for the novel SARS-CoV-2.

机构信息

The Neuro-Lab, School of Health and Health Technology, Federal University of Technology, Akure, Nigeria.

Department of Human Anatomy, School of Health and Health Technology, Federal University of Technology, Akure, Nigeria.

出版信息

Neurol Sci. 2020 Jun;41(6):1329-1337. doi: 10.1007/s10072-020-04469-4. Epub 2020 May 18.

Abstract

Coronaviruses (CoV) are viruses widely known to cause severe respiratory distress due to the prominent clinical symptoms presented. These symptoms, which include fever and dry cough, are frequently found in individuals with CoV infection. Neurological manifestations of CoV have often been neglected; however, recent studies have reported neurological consequences of CoV infection. Here, we review these literatures and discuss the neurologic impact of CoV while highlighting potential implications of the novel SARS-CoV-2 in the nervous system. We also discuss the possible routes by which these viruses invade the nervous system and the mechanism by which they may induce neurological damage.

摘要

冠状病毒(CoV)是众所周知的病毒,由于其突出的临床表现,会导致严重的呼吸道疾病。这些症状包括发热和干咳,在 CoV 感染患者中经常出现。CoV 的神经系统表现常常被忽视;然而,最近的研究报告了 CoV 感染的神经系统后果。在这里,我们复习这些文献,并讨论 CoV 对神经系统的影响,同时强调新型 SARS-CoV-2 对神经系统的潜在影响。我们还讨论了这些病毒入侵神经系统的可能途径以及它们可能导致神经损伤的机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c5a/7232928/d219fb747459/10072_2020_4469_Fig1_HTML.jpg

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