运动不能性缄默症：多巴胺能中脑前额叶激活系统的药理学研究
Akinetic mutism: pharmacologic probe of the dopaminergic mesencephalofrontal activating system.
作者信息
Echiverri H C, Tatum W O, Merens T A, Coker S B
机构信息
Department of Neurology, Loyola University Medical Center, Maywood, IL 60153.
出版信息
Pediatr Neurol. 1988 Jul-Aug;4(4):228-30. doi: 10.1016/0887-8994(88)90036-7.
PMID:3242525
Abstract
Four children who exhibited akinetic mutism during the course of their neurologic diseases were treated with bromocriptine. Reversal of the akinetic mute states was evident in all patients. Pathways of the dopaminergic neurons are reviewed and a clinically useful mechanism which causes akinetic mutism is postulated.
摘要
4例在神经系统疾病病程中出现运动不能性缄默的儿童接受了溴隐亭治疗。所有患者的运动不能性缄默状态均明显逆转。本文回顾了多巴胺能神经元的通路，并提出了一种导致运动不能性缄默的临床有用机制。
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