Mirzapolos Orhay, Marshall Perry, Brill April
Midwestern University, Department of Emergency Medicine, Downers Grove, Illinois.
Clin Pract Cases Emerg Med. 2020 Apr 23;4(2):244-246. doi: 10.5811/cpcem.2020.2.44418. eCollection 2020 May.
Brugada syndrome is an arrhythmogenic disorder that is a known cause of sudden cardiac death. It is characterized by a pattern of ST segment elevation in the precordial leads on an electrocardiogram (EKG) due to a sodium channelopathy.
This case report highlights the case of a five-year-old female who presented to the emergency department with a febrile viral illness and had an EKG consistent with Brugada syndrome.
Fever is known to accentuate or unmask EKG changes associated with Brugada due to temperature sensitivity of the sodium channels.
Febrile patients with Brugada are at particular risk for fatal ventricular arrhythmias and fevers should be treated aggressively by the emergency medicine provider. Emergency medicine providers should also consider admitting febrile patients with Brugada syndrome who do not have an automatic implantable cardioverter-defibrillator for cardiac monitoring.
Brugada综合征是一种致心律失常性疾病,是心脏性猝死的已知原因。其特征是由于钠通道病导致心电图(EKG)胸前导联ST段抬高。
本病例报告重点介绍了一名五岁女性,她因发热性病毒感染就诊于急诊科,其心电图与Brugada综合征相符。
由于钠通道的温度敏感性,已知发热会加重或掩盖与Brugada相关的心电图变化。
患有Brugada综合征的发热患者尤其有发生致命性室性心律失常的风险,急诊医学医生应积极治疗发热。急诊医学医生还应考虑收治没有自动植入式心律转复除颤器的Brugada综合征发热患者进行心脏监测。