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发热诱发的 Brugada 综合征

Brugada syndrome unmasked by fever.

作者信息

Grogan Scott P, Cube Regino P, Edwards John A

机构信息

Department of Family Medicine, Landstuhl Regional Medical Center, CMR 402, P.O. Box 824, APO, AE 09180.

出版信息

Mil Med. 2011 Aug;176(8):946-9. doi: 10.7205/milmed-d-10-00458.

DOI:10.7205/milmed-d-10-00458
PMID:21882788
Abstract

Brugada syndrome (BS) is a cardiac rhythm disturbance that predisposes patients to sudden cardiac death. Brugada is classically described with specific electrocardiographic (EKG) findings of ST elevation and right bundle branch block in precordial leads and is an often unrecognized contributor to sudden cardiac death. We present a case of BS with cyclic EKG findings in a febrile 20-year-old active duty, Vietnamese male who presented following a witnessed syncopal event. His classic findings of Brugada pattern on EKG demonstrated reversibility with clinical defervescence. In patients with a suggestive history, a normal EKG cannot definitively rule out BS as the Brugada pattern can be unmasked by stress, which in this case was represented by a pneumonia-induced fever.

摘要

布加综合征(BS)是一种心律失常疾病,易使患者发生心源性猝死。布加综合征的典型表现是心电图(EKG)胸前导联出现ST段抬高和右束支传导阻滞,它常常是心源性猝死的一个未被认识的原因。我们报告一例20岁发热的越南现役男性布加综合征患者,该患者在一次目击的晕厥事件后就诊,其心电图呈现周期性变化。他心电图上布加综合征的典型表现随着临床退热而可逆。对于有提示性病史的患者,正常心电图不能排除布加综合征,因为布加综合征图形可因应激而显现,在本病例中应激表现为肺炎引起的发热。

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Brugada syndrome unmasked by fever.发热诱发的 Brugada 综合征
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Brugada type 1 electrocardiogram unmasked by a febrile state following syncope.晕厥后发热状态下显露的1型Brugada心电图。
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The definition of the Brugada syndrome.Brugada 综合征的定义。
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Ann Med Surg (Lond). 2024 Jun 19;86(8):4891-4894. doi: 10.1097/MS9.0000000000002286. eCollection 2024 Aug.
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Brugada syndrome unmasked by dengue fever.登革热引发的 Brugada 综合征
Clin Case Rep. 2023 Sep 30;11(10):e8005. doi: 10.1002/ccr3.8005. eCollection 2023 Oct.
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Fever Unmasked Brugada Syndrome in Pediatric Patient: A Case Report.发热揭示小儿患者的 Brugada 综合征:一例报告
Clin Pract Cases Emerg Med. 2020 Apr 23;4(2):244-246. doi: 10.5811/cpcem.2020.2.44418. eCollection 2020 May.
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Arrhythmic events in Brugada syndrome patients induced by fever.发热诱发 Brugada 综合征患者发生心律失常事件。
Ann Noninvasive Electrocardiol. 2020 May;25(3):e12723. doi: 10.1111/anec.12723. Epub 2019 Nov 20.
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Brugada pattern: a comprehensive review on the demographic and clinical spectrum.Brugada波型:关于人口统计学和临床谱的全面综述
BMJ Case Rep. 2019 Jul 11;12(7):e229829. doi: 10.1136/bcr-2019-229829.