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[人胃和大肠腺癌中的鸟氨酸脱羧酶活性及多胺含量]

[Ornithine decarboxylase activity and polyamine content in human adenocarcinomas of the stomach and large intestine].

作者信息

Berdinskikh N K, Zaletok S P, Bobro L I, Ignatenko N A

出版信息

Eksp Onkol. 1988;10(6):39-41.

PMID:3243193
Abstract

Ornithine decarboxylase (ODC) activity and polyamine content were studied in the intact mucosa and tumours of human stomach and large intestine adenocarcinomas. ODC activity has been found to be much higher in the neoplastic tissue than in the corresponding intact mucosa. Concentrations of polyamines in neoplasms were also higher than in mucosa. Interrelation was found between ODC activity polyamine content and degree of differentiation of the tumour cells in rectal adenocarcinomas.

摘要

对人胃和大肠腺癌的完整黏膜及肿瘤组织中的鸟氨酸脱羧酶(ODC)活性和多胺含量进行了研究。已发现肿瘤组织中的ODC活性远高于相应的完整黏膜。肿瘤中的多胺浓度也高于黏膜。在直肠腺癌中,发现ODC活性、多胺含量与肿瘤细胞分化程度之间存在相互关系。

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