Massaras Dimitrios, Pantiora Eirini V, Koutalas John, Primetis Elias C, Fragulidis Georgios P
Surgery, Aretaieio Hospital, National and Kapodistrian University of Athens School of Medicine, Athens, GRC.
Anesthesiology, Aretaieio Hospital, National and Kapodistrian University of Athens School of Medicine, Athens, GRC.
Cureus. 2020 Apr 17;12(4):e7707. doi: 10.7759/cureus.7707.
Serous cystadenocarcinoma of the pancreas is a rare but well-established entity. The origin and evolution of this disorder remain unclear, but even metastatic cases have an excellent prognosis. These tumors are very similar to benign serous cystic neoplasms (SCNs) of the pancreas, except that they tend to be larger, are locally invasive, and present distant metastasis. The most frequent local invasion is adjacent vessels, spleen, stomach, and duodenum. The most common site of distant metastasis is the liver. Diagnosis via imaging as well as pathology examination may be misguided due to atypical characteristics of the tumor. In fact, in some, the diagnosis of malignancy was established only after metastases were detected. We present a 60-year-old female patient with malignant serous microcystic cystadenocarcinoma of the pancreas and liver metastasis that was initially misdiagnosed as a metastatic renal cell carcinoma. The patient underwent tumor resection and liver metastasectomy and she is currently doing well after three years of follow-up, with no tumor recurrence or new metastatic liver nodules based on imaging findings.
胰腺浆液性囊腺癌是一种罕见但已明确的疾病。这种疾病的起源和演变尚不清楚，但即使是转移性病例预后也很好。这些肿瘤与胰腺良性浆液性囊性肿瘤（SCN）非常相似，只是它们往往更大，具有局部侵袭性，并出现远处转移。最常见的局部侵袭部位是相邻血管、脾脏、胃和十二指肠。远处转移最常见的部位是肝脏。由于肿瘤的非典型特征，通过影像学以及病理检查进行诊断可能会产生误导。事实上，在一些病例中，直到检测到转移后才确诊为恶性肿瘤。我们报告一名60岁女性患者，患有胰腺恶性浆液性微囊性囊腺癌并伴有肝转移，最初被误诊为转移性肾细胞癌。该患者接受了肿瘤切除和肝转移灶切除术，经过三年随访，目前情况良好，根据影像学检查结果，没有肿瘤复发或新的肝脏转移结节。
