Thomas Jefferson University, Philadelphia, PA, USA.
Hand (N Y). 2022 Mar;17(2):200-205. doi: 10.1177/1558944720919936. Epub 2020 May 20.
Rates of opioid addiction and overdose continue to climb in the United States, increasing pressure on prescribers to identify solutions to decrease postoperative opioid consumption. Hand and upper extremity surgeries are high-volume surgeries with a predilection for inadvertent overprescribing. Recent investigations have shown that preoperative opioid counseling may decrease postoperative opioid consumption. In order to test this hypothesis, a prospective randomized trial was undertaken to determine the effect of preoperative opioid counseling on postoperative opioid consumption. Eligible patients undergoing outpatient upper extremity surgery were randomized to either receive preoperative opioid counseling or to receive no counseling. Surgeons were blinded to their patient's counseling status. Preoperatively, patient demographics, surgical and prescription details were recorded. Postoperatively, patients' pain experience including opioid consumption, pain levels, and satisfaction was recorded. There were 131 total patients enrolled, with 62 in the counseling group and 69 in the control group. Patients receiving counseling consumed 11.8 pills compared to 17.4 pills in the control group ( = .007), which translated to 93.7 Morphine Equivalent Units (MEU) in the counseling group compared to 143.2 MEU in the control group ( = .01). There was no difference in pain scores at any time point between groups. Among all study patients a total of 3767 opioid pills were prescribed with approximately 50% left unused. Patients receiving preoperative counseling consumed significantly fewer opioids postoperatively. Inadvertant overprescribing remains high. Routine use of preoperative counseling should be implemented along with prescribing fewer opioids overall to prevent overprescribing.
美国阿片类药物成瘾和用药过量的比率持续攀升,这给医生带来了更大的压力,需要寻找减少术后阿片类药物使用量的方法。手部和上肢手术的数量较多,存在无意中过度开药的倾向。最近的调查表明,术前阿片类药物咨询可能会减少术后阿片类药物的使用。为了验证这一假设,进行了一项前瞻性随机试验,以确定术前阿片类药物咨询对术后阿片类药物使用量的影响。
符合条件的门诊上肢手术患者被随机分为接受术前阿片类药物咨询组或不接受咨询组。外科医生对患者的咨询状况不知情。术前记录患者的人口统计学、手术和处方详细信息。术后记录患者的疼痛体验,包括阿片类药物的使用、疼痛水平和满意度。
共有 131 名患者入组,其中 62 名患者接受咨询,69 名患者未接受咨询。接受咨询的患者服用了 11.8 片,而对照组服用了 17.4 片( =.007),这意味着咨询组的 11.8 片相当于 143.2 毫克吗啡等效单位(MEU),而对照组的 17.4 片相当于 143.2 MEU( =.01)。两组在任何时间点的疼痛评分均无差异。在所有研究患者中,共开出了 3767 片阿片类药物,大约有 50%未使用。接受术前咨询的患者术后服用的阿片类药物明显减少。无意中过度开药的情况仍然很高。应常规实施术前咨询,并减少总体阿片类药物的开具量,以防止过度开药。