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Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders.精神障碍的八大类疾病中的基因组关系、新位点和多效机制。
Cell. 2019 Dec 12;179(7):1469-1482.e11. doi: 10.1016/j.cell.2019.11.020.
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How New Technologies Can Improve Prediction, Assessment, and Intervention in Obsessive-Compulsive Disorder (e-OCD): Review.新技术如何改善强迫症(电子强迫症)的预测、评估和干预:综述
JMIR Ment Health. 2019 Dec 10;6(12):e11643. doi: 10.2196/11643.
3
A prospective international multi-center study on safety and efficacy of deep brain stimulation for resistant obsessive-compulsive disorder.一项关于深部脑刺激治疗难治性强迫症安全性和有效性的前瞻性国际多中心研究。
Mol Psychiatry. 2021 Apr;26(4):1234-1247. doi: 10.1038/s41380-019-0562-6. Epub 2019 Oct 29.
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Anterior capsulotomy for obsessive-compulsive disorder: a review of old and new literature.强迫症的前囊切开术:新旧文献综述
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5
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Neuropsychiatr Dis Treat. 2019 Sep 16;15:2663-2669. doi: 10.2147/NDT.S184839. eCollection 2019.
6
Transcranial direct current stimulation in patients with obsessive compulsive disorder: A randomized controlled trial.经颅直流电刺激治疗强迫症患者的随机对照试验。
Eur Psychiatry. 2019 Oct;62:38-44. doi: 10.1016/j.eurpsy.2019.08.011. Epub 2019 Sep 13.
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Continuous theta burst stimulation over the supplementary motor area in refractory obsessive-compulsive disorder treatment: A randomized sham-controlled trial.补充运动区连续 theta 爆发刺激治疗难治性强迫症:一项随机假刺激对照试验。
Brain Stimul. 2019 Nov-Dec;12(6):1565-1571. doi: 10.1016/j.brs.2019.07.019. Epub 2019 Jul 25.
8
Tapering of SSRI treatment to mitigate withdrawal symptoms - Authors' reply.逐渐减少选择性5-羟色胺再摄取抑制剂(SSRI)治疗以减轻戒断症状——作者回复
Lancet Psychiatry. 2019 Jul;6(7):562-563. doi: 10.1016/S2215-0366(19)30219-6.
9
A Clinical Staging Model for Obsessive-Compulsive Disorder: Is It Ready for Prime Time?强迫症的临床分期模型:它准备好成为主流了吗?
EClinicalMedicine. 2019 Feb 12;7:65-72. doi: 10.1016/j.eclinm.2019.01.014. eCollection 2019 Jan.
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BDNF association study with obsessive-compulsive disorder, its clinical characteristics, and response to fluvoxamine-treatment in Iranian patients.BDNF 与强迫症的关联研究,及其在伊朗患者中对氟伏沙明治疗的反应。
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强迫症临床进展:国际强迫症谱系及相关障碍学院立场声明。

Clinical advances in obsessive-compulsive disorder: a position statement by the International College of Obsessive-Compulsive Spectrum Disorders.

机构信息

University of Hertfordshire, Hatfield.

Hertfordshire Partnership University NHS Foundation Trust, Welwyn Garden City, Hertfordshire.

出版信息

Int Clin Psychopharmacol. 2020 Jul;35(4):173-193. doi: 10.1097/YIC.0000000000000314.

DOI:10.1097/YIC.0000000000000314
PMID:32433254
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7255490/
Abstract

In this position statement, developed by The International College of Obsessive-Compulsive Spectrum Disorders, a group of international experts responds to recent developments in the evidence-based management of obsessive-compulsive disorder (OCD). The article presents those selected therapeutic advances judged to be of utmost relevance to the treatment of OCD, based on new and emerging evidence from clinical and translational science. Areas covered include refinement in the methods of clinical assessment, the importance of early intervention based on new staging models and the need to provide sustained well-being involving effective relapse prevention. The relative benefits of psychological, pharmacological and somatic treatments are reviewed and novel treatment strategies for difficult to treat OCD, including neurostimulation, as well as new areas for research such as problematic internet use, novel digital interventions, immunological therapies, pharmacogenetics and novel forms of psychotherapy are discussed.

摘要

在这份立场声明中,国际强迫症谱系障碍学院的一组国际专家针对强迫症(OCD)循证管理的最新进展做出了回应。本文根据临床和转化科学的新出现证据,介绍了那些被认为对 OCD 治疗最相关的选定治疗进展。涵盖的领域包括临床评估方法的精细化、基于新分期模型的早期干预的重要性以及提供涉及有效复发预防的持续幸福感的必要性。还审查了心理、药物和躯体治疗的相对益处,并讨论了针对难治性 OCD 的新治疗策略,包括神经刺激,以及研究的新领域,如问题性互联网使用、新型数字干预、免疫疗法、药物遗传学和新型心理治疗形式。