Passias Peter G, Horn Samantha R, Segreto Frank A, Bortz Cole A, Pierce Katherine E, Vasquez-Montes Dennis, Moon John, Varlotta Christopher G, Raman Tina, Frangella Nicholas J, Stekas Nicholas, Lafage Renaud, Lafage Virginie, Gerling Michael C, Protopsaltis Themistocles S, Buckland Aaron J, Fischer Charla R
NYU Langone Orthopedic Hospital, Manhattan, NY, USA.
Hospital for Special Surgery, Manhattan, NY, USA.
Global Spine J. 2020 Jun;10(4):399-405. doi: 10.1177/2192568219851478. Epub 2019 Jun 9.
Retrospective review of single institution.
To assess the relationship between Patient-Reported Outcomes Measurement Information System (PROMIS) and Oswestry Disability Index (ODI) scores in thoracolumbar patients.
Included: Patients ≥18 years with a thoracolumbar spine condition (spinal stenosis, disc herniation, low back pain, disc degeneration, spondylolysis). Bivariate correlations assessed the linear relationships between ODI and PROMIS (Physical Function, Pain Intensity, and Pain Interference). Correlation cutoffs assessed patients with high and low correlation between ODI and PROMIS. Linear regression predicted the relationship of ODI to PROMIS.
A total of 206 patients (age 53.7 ± 16.6 years, 49.5% female) were included. ODI correlated with PROMIS Physical Function ( = -0.763, < .001), Pain Interference ( = 0.800, < .001), and Pain Intensity ( = 0.706, < .001). ODI strongly predicted PROMIS for Physical Function ( = 0.58, < .001), Pain Intensity ( = 0.50, < .001), and Pain Interference ( = 0.64, < .001); however, there is variability in PROMIS that ODI cannot account for. ODI questions about sitting and sleeping were weakly correlated across the 3 PROMIS domains. Linear regression showed overall ODI score as accounting for 58.3% ( = 0.583) of the variance in PROMIS Physical Function, 63.9% ( = 0.639) of the variance in Pain Interference score, and 49.9% ( = 0.499) of the variance in Pain Intensity score.
There is a large amount of variability with PROMIS that cannot be accounted for with ODI. ODI questions regarding walking, social life, and lifting ability correlate strongly with PROMIS while sitting, standing, and sleeping do not. These results reinforce the utility of PROMIS as a valid assessment for low back disability, while indicating the need for further evaluation of the factors responsible for variation between PROMIS and ODI.
对单一机构进行回顾性研究。
评估胸腰椎疾病患者的患者报告结局测量信息系统（PROMIS）与奥斯威斯利功能障碍指数（ODI）评分之间的关系。
纳入标准：年龄≥18岁的胸腰椎疾病患者（脊柱狭窄、椎间盘突出、腰痛、椎间盘退变、椎弓根峡部裂）。双变量相关性分析评估ODI与PROMIS（身体功能、疼痛强度和疼痛干扰）之间的线性关系。相关性临界值用于评估ODI与PROMIS之间相关性高和低的患者。线性回归分析预测ODI与PROMIS之间的关系。
共纳入206例患者（年龄53.7±16.6岁，49.5%为女性）。ODI与PROMIS身体功能（r = -0.763，P <.001）、疼痛干扰（r = 0.800，P <.001）和疼痛强度（r = 0.706，P <.001）相关。ODI对PROMIS身体功能（β = 0.58，P <.001）、疼痛强度（β = 0.50，P <.001）和疼痛干扰（β = 0.64，P <.001）有较强的预测作用；然而，PROMIS存在一些ODI无法解释的变异性。ODI中关于坐姿和睡眠的问题在PROMIS的三个领域中相关性较弱。线性回归分析显示，总体ODI评分可解释PROMIS身体功能变异的58.3%（R² = 0.583）、疼痛干扰评分变异的63.9%（R² = 0.639）和疼痛强度评分变异的49.9%（R² = 0.499）。
PROMIS存在大量ODI无法解释的变异性。ODI中关于行走、社交生活和提举能力的问题与PROMIS相关性强，而关于坐姿、站姿和睡眠的问题则不然。这些结果强化了PROMIS作为评估下背部功能障碍有效工具的实用性，同时表明需要进一步评估导致PROMIS与ODI之间差异的因素。
