Sharma Mayur, Ugiliweneza Beatrice, Beswick Jennifer, Boakye Maxwell
Department of Neurosurgery, University of Louisville, Louisville, Kentucky, USA.
Department of Neurosurgery, University of Louisville, Louisville, Kentucky, USA.
World Neurosurg. 2018 Jul;115:e664-e675. doi: 10.1016/j.wneu.2018.04.131. Epub 2018 Apr 27.
The aim of our study was to evaluate the change in Patient-Reported Outcome Measurement Information System (PROMIS) scores at baseline, 3 months, and 12 months postprocedure and correlate with legacy measures.
We analyzed patients in 3 cohorts: lumbar, cervical, and the pooled cohort from our database, 2014-2017. Outcome variables were PROMIS items of pain interference, emotional distress and physical function, EuroQol 5 dimensions, visual analog scale, Oswestry Disability Index/Neck Disability Index, back, leg/neck and arm pain scales, and Patient Satisfaction Index.
Patients with lumbar and cervical diseases constituted 55.3% (n = 52) and 44.7% (n = 42) of patients, respectively. There was a significant change in median PROMIS pain interference (65.5 to 57.6), anxiety (56.3 to 48.4), depression (51.2 to 37.1), and physical function (37.2 to 42.6) at baseline and 3 months, respectively. Similarly, change in these scores from baseline to 12 months was significant (n = 48). Compared with change in median Neck Disability Index and Oswestry Disability Index from baseline to 12 months (24.0 to 10.0; P = 0.0004 and 19.0 to 10.0; P < 0.0001), change in median PROMIS physical function score in the same cohort was 38.7 to 45.4 (P = 0.0025) and 37.2 to 41.8 (P < 0.0001), respectively. There was significant correlation between PROMIS pain interference/physical function and the legacy measures at 3 months.
PROMIS items correlated with legacy measures at baseline and postsurgery. Patients undergoing spine surgery improved in their patient-reported outcomes from baseline to 3 months after surgery and the gain were maintained at 12 months.
我们研究的目的是评估患者报告结局测量信息系统（PROMIS）评分在基线、术后3个月和12个月时的变化，并与传统测量指标进行相关性分析。
我们分析了3个队列中的患者：腰椎疾病队列、颈椎疾病队列以及我们数据库（2014 - 2017年）中的合并队列。结局变量包括PROMIS的疼痛干扰、情绪困扰和身体功能项目、欧洲五维健康量表、视觉模拟量表、奥斯维斯特残疾指数/颈部残疾指数、背部、腿部/颈部和手臂疼痛量表以及患者满意度指数。
腰椎疾病患者和颈椎疾病患者分别占患者总数的55.3%（n = 52）和44.7%（n = 42）。基线时和术后3个月，PROMIS疼痛干扰（从65.5降至57.6）、焦虑（从56.3降至48.4）、抑郁（从51.2降至37.1）和身体功能（从37.2升至42.6）的中位数有显著变化。同样，从基线到12个月这些评分的变化也具有显著性（n = 48）。与基线到12个月时颈部残疾指数和奥斯维斯特残疾指数的中位数变化（分别从24.0降至10.0；P = 0.0004和从19.0降至10.0；P < 0.0001）相比，同一队列中PROMIS身体功能评分的中位数变化分别为从38.7升至45.4（P = 0.002）和从37.2升至41.8（P < 0.0001）。术后3个月，PROMIS疼痛干扰/身体功能与传统测量指标之间存在显著相关性。
PROMIS项目在基线和术后与传统测量指标相关。接受脊柱手术的患者在术后3个月时患者报告结局较基线有所改善，且这种改善在12个月时得以维持。
