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老年期心境障碍:安大略省社区居住的老年人群中患病率、风险因素和后果的基于人群分析:老年期心境障碍:安大略省社区居住老年人患病率、风险因素和后果的人群分析。

Mood Disorders in Late Life: A Population-based Analysis of Prevalence, Risk Factors, and Consequences in Community-dwelling Older Adults in Ontario: Troubles de l'humeur en âge avancé : Une analyse dans la population de la prévalence, des facteurs de risque et des conséquences chez des adultes âgés vivant en milieu communautaire en Ontario.

机构信息

Dalla Lana School of Public Health, 7938University of Toronto, Ontario, Canada.

Institute for Clinical Evaluative Sciences (50010ICES), Toronto, Ontario, Canada.

出版信息

Can J Psychiatry. 2020 Sep;65(9):630-640. doi: 10.1177/0706743720927812. Epub 2020 May 21.

Abstract

OBJECTIVE

Mental health issues in late life are a growing public health challenge as the population aged 65 and older rapidly increases worldwide. An updated understanding of the causes of mood disorders and their consequences in late life could guide interventions for this underrecognized and undertreated problem. We undertook a population-based analysis to quantify the prevalence of mood disorders in late life in Ontario, Canada, and to identify potential risk factors and consequences.

METHOD

Individuals aged 65 or older participating in 4 cycles of a nationally representative survey were included. Self-report of a diagnosed mood disorder was used as the outcome measure. Using linked administrative data, we quantified associations between mood disorder and potential risk factors such as demographic/socioeconomic factors, substance use, and comorbidity. We also determined associations between mood disorders and 5-year outcomes including health service utilization and mortality.

RESULTS

The prevalence of mood disorders was 6.1% (4.9% among males, 7.1% among females). Statistically significant associations with mood disorders included younger age, female sex, food insecurity, chronic opioid use, smoking, and morbidity. Individuals with mood disorders had increased odds of all consequences examined, including placement in long-term care (adjusted odds ratio [OR] =2.28; 95% confidence interval [CI], 1.71 to 3.02) and death (adjusted OR = 1.35; 95% CI, 1.13 to 1.63).

CONCLUSIONS

Mood disorders in late life were strongly correlated with demographic and social/behavioral factors, health care use, institutionalization, and mortality. Understanding these relationships provides a basis for potential interventions to reduce the occurrence of mood disorders in late life and their consequences.

摘要

目的

随着全球 65 岁及以上人口的迅速增加,老年人的心理健康问题是一个日益严重的公共卫生挑战。对晚年时期情绪障碍的原因及其后果有更深入的了解,可以为这一未被充分认识和治疗不足的问题提供干预措施。我们进行了一项基于人群的分析,以量化加拿大安大略省老年人中情绪障碍的患病率,并确定潜在的风险因素和后果。

方法

参与全国代表性调查 4 个周期的 65 岁或以上的个体被纳入研究。自我报告的诊断性情绪障碍被用作结局指标。利用关联行政数据,我们量化了情绪障碍与潜在风险因素(如人口统计学/社会经济因素、物质使用和共病)之间的关联。我们还确定了情绪障碍与包括卫生服务利用和死亡率在内的 5 年结局之间的关联。

结果

情绪障碍的患病率为 6.1%(男性为 4.9%,女性为 7.1%)。与情绪障碍有统计学显著关联的因素包括年龄较小、女性、食品无保障、慢性阿片类药物使用、吸烟和发病。患有情绪障碍的个体发生所有后果的可能性增加,包括长期护理安置(调整后的优势比[OR] =2.28;95%置信区间[CI],1.71 至 3.02)和死亡(调整后的 OR = 1.35;95% CI,1.13 至 1.63)。

结论

老年人的情绪障碍与人口统计学和社会/行为因素、卫生保健利用、住院和死亡密切相关。了解这些关系为潜在的干预措施提供了基础,以减少晚年时期情绪障碍的发生及其后果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c182/7485037/204370cdcd85/10.1177_0706743720927812-fig1.jpg

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