Scott J, Woods K, Baxter P
School of Dental Surgery, University of Liverpool, U.K.
J Biol Buccale. 1988 Dec;16(4):215-8.
Stimulated and unstimulated parotid salivas were examined in a series of non-cirrhotic patients under treatment for alcohol dependence and in age-sex matched, non-alcoholic, healthy, control subjects. Resting salivary flow was raised threefold in the alcohol group and the protein and electrolyte concentrations were also altered in this saliva. However, there were no intergroup differences in parotid flow or composition following gustatory stimulation by 6% citric acid. The results contrast with the wide parotid functional changes known to occur in stimulated parotid saliva in alcoholic cirrhosis and suggest, therefore, that the direct salivary effects of chronic alcohol abuse may be less important than the damaged liver function in contributing to the salivary disturbance reportedly occurring in alcoholic cirrhosis.
在一系列接受酒精依赖治疗的非肝硬化患者以及年龄和性别匹配的非酒精性健康对照受试者中，对刺激和未刺激的腮腺唾液进行了检查。酒精组的静息唾液流量增加了两倍，且该唾液中的蛋白质和电解质浓度也发生了变化。然而，用6%柠檬酸进行味觉刺激后，两组之间腮腺流量或成分没有差异。这些结果与酒精性肝硬化患者刺激腮腺唾液中已知发生的广泛腮腺功能变化形成对比，因此表明，在导致酒精性肝硬化中据报道出现的唾液紊乱方面，慢性酒精滥用对唾液的直接影响可能不如受损的肝功能重要。
