Institute of Nursing and Health, College of Nursing and Health, Henan University, Jinming Avenue, Kaifeng, Henan, 475004, China.
School of Business, Henan University, Jinming Avenue, Kaifeng, Henan, 475004, China.
Psychiatry Res. 2020 Jul;289:113002. doi: 10.1016/j.psychres.2020.113002. Epub 2020 May 7.
In this study, we evaluated the efficacy of mindfulness-based stress reduction (MBSR) for young people with anxiety symptoms. We used many databases, including PubMed, PsycINFO, Web of Science, EMBASE, CINAHL and Cochrane Library (from inception to May 2019). We included randomized controlled trials (RCTs) comparing MBSR with various control conditions, including didactic lecture course, health education, treatment as usual, didactic seminar and cognitive behavioral program in young people with anxiety symptoms. Finally, we selected fourteen studies comprising 1489 participants comparing with control conditions. The meta-analysis suggested that MBSR significantly reduced anxiety symptoms compared to control conditions at post-treatment (Standardized Mean Difference, SMD = -0.14, 95% CI -0.24 to -0.04). However, the effect of MBSR on anxiety symptoms in young people may be affected by different intervention duration, especially the significance in a short-term intervention (less than 8 weeks). In addition, the meta-analysis indicated publication bias for anxiety symptoms. Using the trim-and-fill method, we found the adjusted standardized mean difference, which indicated that MBSR was still significantly superior to the other control conditions. The sensitivity analysis showed that the result was reliable. Current evidence indicates MBSR has superior efficacy compared with control conditions in treating young people with anxiety symptoms. Based on this, we suggest there is a significant effect of MBSR on young people with anxiety symptoms, especially the effects of long-term intervention for future studies.
在这项研究中，我们评估了正念减压疗法（MBSR）对有焦虑症状的年轻人的疗效。我们使用了许多数据库，包括 PubMed、PsycINFO、Web of Science、EMBASE、CINAHL 和 Cochrane Library（从创建到 2019 年 5 月）。我们纳入了比较 MBSR 与各种对照条件（包括讲座课程、健康教育、常规治疗、专题研讨会和认知行为方案）的随机对照试验（RCT），这些对照条件用于有焦虑症状的年轻人。最后，我们选择了 14 项研究，共纳入 1489 名参与者，与对照条件进行比较。荟萃分析表明，与对照条件相比，MBSR 治疗后焦虑症状显著减轻（标准化均数差，SMD=-0.14，95%置信区间-0.24 至-0.04）。然而，MBSR 对年轻人焦虑症状的影响可能会受到不同干预持续时间的影响，特别是短期干预（少于 8 周）的效果。此外，荟萃分析表明焦虑症状存在发表偏倚。使用修剪和填充法，我们发现了调整后的标准化均数差，这表明 MBSR 仍然明显优于其他对照条件。敏感性分析表明结果是可靠的。目前的证据表明，MBSR 与对照条件相比，在治疗有焦虑症状的年轻人方面具有更好的疗效。基于此，我们建议 MBSR 对有焦虑症状的年轻人有显著的影响，特别是对未来研究中长期干预的效果。
