Silva Ángela, Gonzalez Nuria, Terrén Ana, García Antonio, Martinez-Blanch Juan Francisco, Illescas Vanessa, Morales Javier, Maroto Marcos, Genovés Salvador, Ramón Daniel, Martorell Patricia, Chenoll Empar
Health & Wellness-ADM Nutrition-ADM Biopolis, 46980 Paterna, Spain.
Instituto Fundación Teófilo Hernando, 28029 Madrid, Spain.
Foods. 2020 May 19;9(5):652. doi: 10.3390/foods9050652.
Pediatric obesity has a growing health and socio-economical impact due to cardiovascular and metabolic complications in adult life. Some recent studies suggest that live or heat-treated probiotics have beneficial effects in preventing fat deposition and obesity in preclinical and clinical sets. Here, we have explored the effects of heat-treated probiotic subsp. CECT 8145 (HT-BPL1), added as a supplement on an infant milk formula (HT-BPL1-IN), on fat deposition and short-chain fatty acids (SCFAs) and lactate, using fermented baby fecal slurries. We have found that HT-BPL1-IN significantly reduced fat deposition in at the time it drastically augmented the generation of some SCFAs, particulary acetate and organic acid lactate. Data suggest that heat-treated BPL1 maintains its functional activities when added to an infant powder milk formula.
由于成年期心血管和代谢并发症,儿童肥胖对健康和社会经济的影响日益增大。最近的一些研究表明,活的或经过热处理的益生菌在临床前和临床环境中对预防脂肪沉积和肥胖具有有益作用。在此,我们使用发酵的婴儿粪便浆液,探讨了作为补充剂添加到婴儿配方奶粉(HT-BPL1-IN)中的热处理益生菌亚种CECT 8145(HT-BPL1)对脂肪沉积、短链脂肪酸(SCFAs)和乳酸的影响。我们发现,HT-BPL1-IN在显著增加某些SCFAs(特别是乙酸盐和有机酸乳酸)生成的同时,显著减少了脂肪沉积。数据表明,热处理的BPL1添加到婴儿奶粉配方中时仍保持其功能活性。