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冰岛 20 多年来的意外中毒、故意自残和意图不明的死亡事件:一项基于人群的队列研究。

Accidental poisoning, intentional self-harm and event of undetermined intent mortality over 20 years in Iceland: a population-based cohort study.

机构信息

Office of Education, Research and Development, Landspitali-the National University Hospital of Iceland, Reykjavík, Iceland.

Department of Preventive Medicine, Faculty of Medicine, University of Iceland, Reykjavík, Iceland

出版信息

BMJ Open. 2020 May 20;10(5):e034590. doi: 10.1136/bmjopen-2019-034590.

Abstract

OBJECTIVES

The aim was to study mortality due to suicide, accidental poisoning, event of undetermined intent and drug-related deaths through 20 years in Iceland.

DESIGN

A population-based register study.

PARTICIPANTS

Individuals who died due to road traffic injury, suicide, accidental poisoning, event of undetermined intent and drug-related deaths in the population of Iceland during the years 1996-2015. Annual age-standardised rates were calculated, and the trend analysed by Pearson correlation and joinpoint regression.

SETTING

The population of Iceland framed the study material, and the data were obtained from nationwide registries for information on number of deaths and age-specific mean population in each year by gender.

RESULTS

The crude overall suicide rate during the last 10 years was 12.2 per 100 000 persons per year (95% CI 7.4 to 18.1), while the crude overall rate due to road traffic injuries was 4.6 per 100 000 persons per year (95% CI 2.0 to 8.3). Among men, suicide rates decreased, however not significantly (r(19)=-0.22, p=0.36), and for overdose by narcotics the rates increased significantly (r(19)=0.72, p<0.001) during the study period. Among women, the suicide rates increased, however not significantly (r(19)=0.35, p=0.13), for accidental poisoning, suicide and event of undetermined intent combined the rates increased significantly (r(19)=0.60, p=0.006); and the rates for overdose by sedative and overdose by narcotics both increased significantly r(19)=0.49, p=0.03, and r(19)=0.67, p=0.001, respectively.

CONCLUSION

The suicide rates have not changed during 1996 to 2015; however, the rates for the combined accidental poisoning, suicide and event of undetermined intent increased significantly for women. The rise of the overdose rates for sedative among women and for narcotics among both genders are consistent with reports elsewhere.

摘要

目的

研究 1996 年至 2015 年期间冰岛因自杀、意外中毒、意图不明事件和药物相关死亡导致的死亡率。

设计

基于人群的登记研究。

参与者

1996 年至 2015 年期间因道路交通伤害、自杀、意外中毒、意图不明事件和药物相关死亡的冰岛人群中的个体。计算了每年的年龄标准化率,并通过 Pearson 相关分析和连接点回归分析趋势。

设置

冰岛人群构成了研究材料,数据来自全国登记册,用于获取每年按性别和年龄特定的死亡人数和平均人口信息。

结果

过去 10 年的粗自杀率为每年每 10 万人 12.2 例(95%CI 7.4 至 18.1),而粗道路交通伤害死亡率为每年每 10 万人 4.6 例(95%CI 2.0 至 8.3)。男性自杀率下降,但无统计学意义(r(19)=-0.22,p=0.36),而麻醉品过量的死亡率显著上升(r(19)=0.72,p<0.001)。女性自杀率升高,但无统计学意义(r(19)=0.35,p=0.13),意外中毒、自杀和意图不明事件的合并死亡率显著升高(r(19)=0.60,p=0.006);镇静剂过量和麻醉品过量的死亡率均显著升高(r(19)=0.49,p=0.03 和 r(19)=0.67,p=0.001)。

结论

1996 年至 2015 年期间自杀率没有变化;然而,女性因意外中毒、自杀和意图不明事件导致的合并死亡率显著升高。女性镇静剂过量和两性麻醉品过量的发生率上升与其他地方的报告一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4069/7247372/df5ebe4d6cc6/bmjopen-2019-034590f01.jpg

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