Department of Orthopedics and Traumatology, Saiful Anwar General Hospital-Universitas Brawijaya, Malang, Indonesia.
Department of Pathology, Saiful Anwar General Hospital-Universitas Brawijaya, Malang, Indonesia.
Am J Case Rep. 2020 May 22;21:e922257. doi: 10.12659/AJCR.922257.
BACKGROUND Osteosarcoma is the most common type of malignant bone tumor arising from mesenchymal stem cell. When occurring on the proximal humerus, it is associated with poor outcomes; there are numerous neurovascular structures around proximal humerus. Unfortunately, the degree of vascular involvement in osteosarcoma is rarely evaluated and reported. Thus, we would like to highlight our case. CASE REPORT We reported a case of left proximal humerus osteosarcoma causing dead limb in a 14-year-old boy. The dead limb progressed in the span of 3 weeks. An emergency forequarter amputation (FQA) was conducted to prevent further complications such as septicemia and mortality. Two months after the surgery, the patient had improved quality of life. One year after, the patient had no local recurrence. However, there was a lung metastasis detected 9 months after the surgery. The patient died 13 months after the surgery. CONCLUSIONS Osteosarcoma of the proximal humerus can potentially compromise vascular structures. Early diagnosis and treatment are mandatory to prevent such complications.
成骨肉瘤是最常见的源自间充质干细胞的恶性骨肿瘤。发生在肱骨近端时，预后较差；肱骨近端周围有许多神经血管结构。不幸的是，成骨肉瘤中血管受累的程度很少被评估和报告。因此，我们想强调一下我们的病例。
我们报告了一例 14 岁男孩左侧肱骨近端成骨肉瘤导致肢体坏死的病例。该肢体坏死在 3 周内进展。为了防止败血症和死亡等进一步并发症，进行了紧急前肢截肢术（FQA）。手术后两个月，患者的生活质量得到了改善。一年后，患者无局部复发。然而，手术后 9 个月发现了肺转移。手术后 13 个月，患者死亡。
肱骨近端成骨肉瘤可能会损害血管结构。早期诊断和治疗是预防此类并发症的必要措施。
