• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

非剥脱性分次激光与脉冲染料激光在预防甲状腺切除术后瘢痕方面的有效性比较。

Comparison of the Effectiveness of Nonablative Fractional Laser versus Pulsed-Dye Laser in Thyroidectomy Scar Prevention.

作者信息

Ha Ji Min, Kim Han Su, Cho Eun Byul, Park Gyeong Hun, Park Eun Joo, Kim Kwang Ho, Kim Lee Su, Kim Kwang Joong

机构信息

Department of Dermatology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.

Department of Dermatology, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Korea.

出版信息

Ann Dermatol. 2014 Oct;26(5):615-20. doi: 10.5021/ad.2014.26.5.615. Epub 2014 Sep 26.

DOI:10.5021/ad.2014.26.5.615
PMID:25324655
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4198590/
Abstract

BACKGROUND

The anterior neck is the site of open thyroidectomy and where postoperative scarring can cause distress to patients. Both fractional and pulsed-dye lasers are effective and safe methods for preventing and improving surgical scars.

OBJECTIVE

This study evaluated the improvement in scar appearance with laser intervention during the wound healing process. We evaluated the effect of nonablative fractional and pulsed-dye lasers on fresh thyroidectomy scars.

METHODS

Patients were treated 3 times at 4-week interval with a follow-up visit at the 6(th) month. Scars were divided into 2 halves for each optional treatment. At every visit, a questionnaire evaluating the scar and patient satisfaction was completed.

RESULTS

Thirty patients completed the 6-month process. The mean Vancouver Scar Scale scores improved significantly from 8.0 to 4.6 and 8.2 to 4.7 with nonablative fractional and pulsed-dye lasers, respectively (p<0.001). However, there was no significant difference between the 2 methods (p=0.840).

CONCLUSION

There remains no consensus on the optimal treatment of scars. The present study indicates nonablative fractional and pulsed-dye lasers significantly improve scars. Nonablative fractional lasers are non-inferior to pulsed-dye lasers. Further studies are required to corroborate this finding.

摘要

背景

颈部前方是开放性甲状腺切除术的手术部位,术后瘢痕可能给患者带来困扰。分次激光和脉冲染料激光都是预防和改善手术瘢痕的有效且安全的方法。

目的

本研究评估了在伤口愈合过程中激光干预对瘢痕外观的改善情况。我们评估了非剥脱性分次激光和脉冲染料激光对新鲜甲状腺切除术后瘢痕的效果。

方法

患者每隔4周接受3次治疗,并在第6个月进行随访。每次治疗时,将瘢痕分为两半进行任意一种治疗。每次随访时,完成一份评估瘢痕和患者满意度的问卷。

结果

30例患者完成了6个月的治疗过程。非剥脱性分次激光和脉冲染料激光治疗后,温哥华瘢痕量表平均评分分别从8.0显著改善至4.6和从8.2显著改善至4.7(p<0.001)。然而,两种方法之间无显著差异(p=0.840)。

结论

关于瘢痕的最佳治疗方法尚无共识。本研究表明,非剥脱性分次激光和脉冲染料激光能显著改善瘢痕。非剥脱性分次激光不劣于脉冲染料激光。需要进一步研究来证实这一发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0cf/4198590/a04d400771f1/ad-26-615-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0cf/4198590/8cbc1480f0b4/ad-26-615-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0cf/4198590/fbd204a6e632/ad-26-615-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0cf/4198590/b8811f8636a7/ad-26-615-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0cf/4198590/b60f4b4c84d8/ad-26-615-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0cf/4198590/b920b7571fbf/ad-26-615-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0cf/4198590/a04d400771f1/ad-26-615-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0cf/4198590/8cbc1480f0b4/ad-26-615-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0cf/4198590/fbd204a6e632/ad-26-615-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0cf/4198590/b8811f8636a7/ad-26-615-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0cf/4198590/b60f4b4c84d8/ad-26-615-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0cf/4198590/b920b7571fbf/ad-26-615-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0cf/4198590/a04d400771f1/ad-26-615-g006.jpg

相似文献

1
Comparison of the Effectiveness of Nonablative Fractional Laser versus Pulsed-Dye Laser in Thyroidectomy Scar Prevention.非剥脱性分次激光与脉冲染料激光在预防甲状腺切除术后瘢痕方面的有效性比较。
Ann Dermatol. 2014 Oct;26(5):615-20. doi: 10.5021/ad.2014.26.5.615. Epub 2014 Sep 26.
2
Comparison of the effectiveness of nonablative fractional laser versus ablative fractional laser in thyroidectomy scar prevention: A pilot study.非剥脱性分次激光与剥脱性分次激光预防甲状腺切除术后瘢痕效果的比较:一项初步研究。
J Cosmet Laser Ther. 2012 Apr;14(2):89-93. doi: 10.3109/14764172.2012.672746.
3
Comparison of the Effectiveness of Ablative and Non-Ablative Fractional Laser Treatments for Early Stage Thyroidectomy Scars.消融性与非消融性剥脱性激光治疗早期甲状腺切除术后瘢痕的疗效比较
Arch Plast Surg. 2016 Nov;43(6):575-581. doi: 10.5999/aps.2016.43.6.575. Epub 2016 Nov 18.
4
Laser treatments in early wound healing improve scar appearance: a randomized split-wound trial with nonablative fractional laser exposures vs. untreated controls.早期伤口愈合中的激光治疗可改善疤痕外观:非剥脱性点阵激光与未治疗对照的随机分割伤口试验。
Br J Dermatol. 2018 Dec;179(6):1307-1314. doi: 10.1111/bjd.17076. Epub 2018 Sep 30.
5
Treatment of surgical scars with nonablative fractional laser versus pulsed dye laser: a randomized controlled trial.非剥脱性分次激光与脉冲染料激光治疗手术瘢痕:一项随机对照试验。
Dermatol Surg. 2009 Aug;35(8):1172-80. doi: 10.1111/j.1524-4725.2009.01085.x. Epub 2009 Feb 23.
6
Comparison of the effectiveness of pulsed dye laser vs pulsed dye laser combined with ultrapulse fractional CO laser in the treatment of immature red hypertrophic scars.脉冲染料激光与脉冲染料激光联合超脉冲分数CO2激光治疗未成熟红色增生性瘢痕的疗效比较。
J Cosmet Dermatol. 2018 Feb;17(1):54-60. doi: 10.1111/jocd.12487.
7
1550-nm Nonablative Fractional Laser Versus 10,600-nm Ablative Fractional Laser in the Treatment of Surgical and Traumatic Scars: A Comparison Study on Efficacy and Treatment Regimen.1550nm 非剥脱性点阵激光与 10600nm 剥脱性点阵激光治疗手术和外伤性瘢痕的疗效和治疗方案比较研究。
Dermatol Surg. 2020 Jun;46(6):780-788. doi: 10.1097/DSS.0000000000002152.
8
The Outcome of Early Ablative Fractional Laser Treatment for Thyroidectomy Scars.早期消融性激光治疗甲状腺切除术瘢痕的结果。
Lasers Surg Med. 2020 Oct;52(8):721-729. doi: 10.1002/lsm.23217. Epub 2020 Jan 16.
9
[Clinical comparative study of pulsed dye laser and ultra-pulsed fractional carbon dioxide laser in the treatment of hypertrophic scars after burns].脉冲染料激光与超脉冲分次二氧化碳激光治疗烧伤后增生性瘢痕的临床对比研究
Zhonghua Shao Shang Za Zhi. 2018 Sep 20;34(9):603-607. doi: 10.3760/cma.j.issn.1009-2587.2018.09.009.
10
595-nm pulsed dye laser combined with fractional CO laser reduces hypertrophic scar through down-regulating TGFβ1 and PCNA.595nm 脉冲染料激光联合点阵 CO2 激光通过下调 TGFβ1 和 PCNA 减少增生性瘢痕。
Lasers Med Sci. 2021 Oct;36(8):1625-1632. doi: 10.1007/s10103-020-03240-7. Epub 2021 Jun 12.

引用本文的文献

1
Fractional 1064 nm Nd: YAG picosecond lasers for the treatment of traumatic scars: a retrospective study.用于治疗创伤性瘢痕的1064纳米掺钕钇铝石榴石皮秒分数激光:一项回顾性研究。
Lasers Med Sci. 2024 Dec 28;40(1):1. doi: 10.1007/s10103-024-04247-0.
2
Early postoperative interventions in the prevention and management of thyroidectomy scars.甲状腺切除术后瘢痕预防与处理的早期干预措施
Front Physiol. 2024 Mar 6;15:1341287. doi: 10.3389/fphys.2024.1341287. eCollection 2024.
3
Combination therapy using non-ablative fractional laser and intralesional triamcinolone injection for hypertrophic scars and keloids treatment.

本文引用的文献

1
Appropriate timing for thyroidectomy scar treatment using a 1,550-nm fractional erbium-glass laser.采用 1550nm 飞秒铒玻璃激光治疗甲状腺切除术瘢痕的适宜时机。
Dermatol Surg. 2013 Dec;39(12):1827-34. doi: 10.1111/dsu.12355. Epub 2013 Nov 7.
2
Pulsed dye laser for the treatment of keloid and hypertrophic scars: a systematic review.脉冲染料激光治疗瘢痕疙瘩和增生性瘢痕:系统评价。
Expert Rev Med Devices. 2012 Nov;9(6):641-50. doi: 10.1586/erd.12.56.
3
Comparison of the effectiveness of nonablative fractional laser versus ablative fractional laser in thyroidectomy scar prevention: A pilot study.
联合应用非剥脱性点阵激光和局部注射曲安奈德治疗增生性瘢痕和瘢痕疙瘩。
Int Wound J. 2019 Dec;16(6):1450-1456. doi: 10.1111/iwj.13213. Epub 2019 Sep 2.
4
Fractional CO laser treatment for post-surgical lip scars in cleft lip and palate patients.分束 CO2 激光治疗唇裂腭裂术后唇瘢痕
Lasers Med Sci. 2019 Oct;34(8):1699-1703. doi: 10.1007/s10103-019-02819-z. Epub 2019 Jun 11.
5
Early intervention with pulse dye and CO ablative fractional lasers to improve cutaneous scarring post-lumpectomy: a randomized controlled trial on the impact of intervention on final cosmesis.早期应用脉冲染料和 CO2 消融性点阵激光改善保乳术后皮肤瘢痕:一项关于干预对最终美容效果影响的随机对照试验。
Lasers Med Sci. 2019 Dec;34(9):1881-1887. doi: 10.1007/s10103-019-02788-3. Epub 2019 Apr 26.
6
[Therapy of scars with lasers].[激光治疗瘢痕]
Hautarzt. 2018 Jan;69(1):17-26. doi: 10.1007/s00105-017-4072-7.
7
Postoperative Treatment of Linear Thyroidectomy Scars with the Pinhole Method Using a 10600-nm Carbon Dioxide Laser.使用10600纳米二氧化碳激光针孔法对甲状腺线性切除术疤痕进行术后治疗
Yonsei Med J. 2016 Nov;57(6):1540-1. doi: 10.3349/ymj.2016.57.6.1540.
非剥脱性分次激光与剥脱性分次激光预防甲状腺切除术后瘢痕效果的比较:一项初步研究。
J Cosmet Laser Ther. 2012 Apr;14(2):89-93. doi: 10.3109/14764172.2012.672746.
4
Effect of the 595-nm pulsed dye laser and ablative 2940-nm Er:YAG fractional laser on fresh surgical scars: an uncontrolled pilot study.595纳米脉冲染料激光和剥脱性2940纳米铒:钇铝石榴石点阵激光对新鲜手术瘢痕的影响:一项非对照性初步研究。
J Cosmet Laser Ther. 2011 Aug;13(4):176-9. doi: 10.3109/14764172.2011.594061. Epub 2011 Jun 30.
5
Current tools for noninvasive objective assessment of skin scars.目前用于非侵入性客观评估皮肤疤痕的工具。
Plast Reconstr Surg. 2010 Sep;126(3):912-923. doi: 10.1097/PRS.0b013e3181e6046b.
6
Complications of fractional CO2 laser resurfacing: four cases.二氧化碳点阵激光换肤术的并发症:4例报告
Lasers Surg Med. 2009 Mar;41(3):179-84. doi: 10.1002/lsm.20753.
7
Fractional photothermolysis: a review and update.点阵激光:综述与更新
Semin Cutan Med Surg. 2008 Mar;27(1):63-71. doi: 10.1016/j.sder.2008.01.002.
8
Hypertrophic scars and keloids: etiology and management.增生性瘢痕与瘢痕疙瘩:病因及治疗
Am J Clin Dermatol. 2003;4(4):235-43. doi: 10.2165/00128071-200304040-00003.
9
585-nm pulsed dye laser in the treatment of surgical scars starting on the suture removal day.585纳米脉冲染料激光在缝线拆除当日开始治疗手术瘢痕。
Dermatol Surg. 2003 Jan;29(1):65-73; discussion 73. doi: 10.1046/j.1524-4725.2003.29014.x.