Abdollahimajd Fahimeh, Shahidi-Dadras Mohammad, M Robati Reza, Dadkhahfar Sahar
Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Dermatology, Loghman Hakim Hospital, Shahid Beheshti of Medical Sciences.
Arch Acad Emerg Med. 2020 Apr 18;8(1):e51. eCollection 2020.
The novel coronavirus is rapidly spreading around the world. Since the public announcement of the COVID-19 outbreak, several concerns have been raised by dermatologists as well as pemphigus patients who take immunosuppressive drugs. In this paper, we review the literature about the common treatment of pemphigus with a focus on the lessons from similar epidemics to find a proper suggestion to manage pemphigus in the COVID-19 pandemic era. The effect of many of the drugs used for treatment of Pemphigus vulgaris (PV) on COVID-19 is not clear. We also do not have data on the impact of this autoimmune disease, which may involve the mucous membranes, on the acquisition or course of COVID-19. We are currently in the midst of a pandemic and evaluating the effect of COVID-19 on the population of susceptible patients suffering from auto-immune diseases like pemphigus is essential. The evidence on best ways to manage patients with underlying conditions, such as pemphigus, during the outbreak of COVID-19 is evolving and the data is updated every day.
新型冠状病毒正在全球迅速传播。自新冠疫情公开通报以来,皮肤科医生以及服用免疫抑制药物的天疱疮患者提出了若干担忧。在本文中,我们回顾了关于天疱疮常见治疗方法的文献,重点关注从类似疫情中吸取的经验教训,以便在新冠疫情时代找到管理天疱疮的适当建议。许多用于治疗寻常型天疱疮(PV)的药物对新冠病毒的影响尚不清楚。我们也没有关于这种可能累及黏膜的自身免疫性疾病对新冠病毒感染或病程影响的数据。我们目前正处于大流行之中,评估新冠病毒对天疱疮等自身免疫性易感患者群体的影响至关重要。在新冠疫情爆发期间,关于管理患有天疱疮等基础疾病患者的最佳方法的证据正在不断发展,数据每天都在更新。