Sawyers J L, Herrington J L
Ann Surg. 1977 Jun;185(6):656-60. doi: 10.1097/00000658-197706000-00007.
Twenty-one patients with acute perforated duodenal ulcer were managed by proximal gastric vagotomy without drainage and simple closure of the perforation reinforced with an omental patch. There was no operative mortality. No recurrent duodenal ulcers have developed. All patients have achieved a good to excellent clinical result from their operation. Dumping, diarrhea, and reflux gastritis have not developed. Follow-up studies extend to three and one-half years. Proximal gastric vagotomy with simple closure is safe, effective management for the patient with an acute perforated duodenal ulcer. This operation is a satisfactory compromise between simple closure alone which does not protect against recurrent ulcer and definitive ulcer operations which may subject patients who would not have further ulcer symptoms to the unnecessary risk of increased mortality, morbidity, and postgastrectomy disorders.
21例急性十二指肠溃疡穿孔患者接受了近端胃迷走神经切断术,未行引流,仅单纯缝合穿孔,并加用网膜补片加固。无手术死亡病例。未发生复发性十二指肠溃疡。所有患者术后临床效果良好至极佳。未出现倾倒综合征、腹泻和反流性胃炎。随访研究长达三年半。单纯缝合加近端胃迷走神经切断术对急性十二指肠溃疡穿孔患者是一种安全、有效的治疗方法。该手术是单纯缝合(不能预防复发性溃疡)与确定性溃疡手术(可能使不会再有溃疡症状的患者面临不必要的死亡风险增加、发病率增加和胃切除术后并发症风险)之间的一种令人满意的折衷方案。