Qiao Xiao-Feng, Xue Yu, Liu Shi-Chen, Ji Qing-Hui
First Ward of Orthopedis Department, First Affiliated Hospital of Jiamusi University.
Department of Obstetrics and Gynecology, Second Affiliated Hospital of Jiamusi University, Jiamusi, China.
Medicine (Baltimore). 2020 May;99(20):e20259. doi: 10.1097/MD.0000000000020259.
Femoral head avascular necrosis (FHAN) is a very common condition among elderly population. Previous studies have reported that total hip arthroplasty (THAP) can benefit patients with such condition. However, no study systematically addressed this topic. Thus, this study will systematically explore the efficacy and safety of THAP for the treatment of patients with FHAN.
We will search the following electronic bibliographic databases from inception to the February 29, 2020: MEDLINE, EMBASE, Cochrane Library, Cumulative Index to Nursing and Allied Health Literature, China National Knowledge Infrastructure, and Chinese Scientific Journal Database. Randomized controlled trials of THAP for the treatment of patients with FHAN will be included, which were reported in any language. All process of study selection, data collection, and study quality assessment will be performed independently by 2 authors independently. Any divergences will be solved by discussion with another author. RevMan 5.3 software will be carried out for data synthesis and analysis.
This study will provide a detailed summary of current evidence related to the efficacy and safety of THAP for the treatment of patients with FHAN through assessing pain intensity of hip or knee joints, function and limitation of attacked femoral head, health-related quality of life, and complications.
The findings of this study may provide helpful guidance of THAP for the treatment of patients with FHAN.
INPLASY202040067.
股骨头缺血性坏死（FHAN）在老年人群中非常常见。既往研究报道全髋关节置换术（THAP）可使患有这种疾病的患者受益。然而，尚无研究系统地探讨这一主题。因此，本研究将系统地探究THAP治疗FHAN患者的疗效和安全性。
我们将检索从建库至2020年2月29日的以下电子文献数据库：医学主题词表（MEDLINE）、荷兰医学文摘数据库（EMBASE）、考克兰图书馆、护理学与健康照护领域累积索引数据库、中国知网以及中国科学期刊数据库。将纳入以任何语言报道的关于THAP治疗FHAN患者的随机对照试验。研究选择、数据收集和研究质量评估的所有过程将由2位作者独立进行。任何分歧将通过与另一位作者讨论解决。将使用RevMan 5.3软件进行数据合成与分析。
本研究将通过评估髋关节或膝关节的疼痛强度、受累股骨头的功能和受限情况、健康相关生活质量以及并发症，详细总结目前与THAP治疗FHAN患者的疗效和安全性相关的证据。
本研究结果可能为THAP治疗FHAN患者提供有益的指导。
INPLASY202040067。
