Nazhand Amirhossein, Durazzo Alessandra, Lucarini Massimo, Souto Eliana B, Santini Antonello
Department of Biotechnology, Sari Agricultural Science and Natural Resource University, 9th km of Farah Abad Road, Mazandaran 48181-68984, Iran.
CREA-Research Centre for Food and Nutrition, Via Ardeatina 546, 00178 Roma, Italy.
Foods. 2020 May 18;9(5):644. doi: 10.3390/foods9050644.
Mycotoxin contamination continues to be a food safety concern globally, with the most toxic being aflatoxins. On-farm aflatoxins, during food transit or storage, directly or indirectly result in the contamination of foods, which affects the liver, immune system and reproduction after infiltration into human beings and animals. There are numerous reports on aflatoxins focusing on achieving appropriate methods for quantification, precise detection and control in order to ensure consumer safety. In 2012, the International Agency for Research on Cancer (IARC) classified aflatoxins B1, B2, G1, G2, M1 and M2 as group 1 carcinogenic substances, which are a global human health concern. Consequently, this review article addresses aflatoxin chemical properties and biosynthetic processes; aflatoxin contamination in foods and feeds; health effects in human beings and animals due to aflatoxin exposure, as well as aflatoxin detection and detoxification methods.
霉菌毒素污染仍是全球食品安全领域关注的问题,其中毒性最强的是黄曲霉毒素。农场中的黄曲霉毒素在食品运输或储存过程中直接或间接导致食品污染,这些毒素侵入人和动物体内后会影响肝脏、免疫系统及生殖系统。关于黄曲霉毒素的报道众多,主要集中在寻求合适的定量方法、精确检测和控制手段以确保消费者安全。2012年,国际癌症研究机构(IARC)将黄曲霉毒素B1、B2、G1、G2、M1和M2列为1类致癌物,这是一个全球人类健康问题。因此,这篇综述文章探讨了黄曲霉毒素的化学性质和生物合成过程;食品和饲料中的黄曲霉毒素污染情况;黄曲霉毒素暴露对人和动物健康的影响,以及黄曲霉毒素的检测和解毒方法。