Spychalska Kamila, Zając Dorota, Baluta Sylwia, Halicka Kinga, Cabaj Joanna
Faculty of Chemistry, Wrocław University of Science and Technology, 50-137 Wrocław, Poland.
Polymers (Basel). 2020 May 18;12(5):1154. doi: 10.3390/polym12051154.
In this review we present polymeric materials for (bio)sensor technology development. We focused on conductive polymers (conjugated microporous polymer, polymer gels), composites, molecularly imprinted polymers and their influence on the design and fabrication of bio(sensors), which in the future could act as lab-on-a-chip (LOC) devices. LOC instruments enable us to perform a wide range of analysis away from the stationary laboratory. Characterized polymeric species represent promising candidates in biosensor or sensor technology for LOC development, not only for manufacturing these devices, but also as a surface for biologically active materials' immobilization. The presence of biological compounds can improve the sensitivity and selectivity of analytical tools, which in the case of medical diagnostics is extremely important. The described materials are biocompatible, cost-effective, flexible and are an excellent platform for the anchoring of specific compounds.
在本综述中,我们介绍了用于(生物)传感器技术开发的聚合物材料。我们重点关注导电聚合物(共轭微孔聚合物、聚合物凝胶)、复合材料、分子印迹聚合物及其对生物(传感器)设计和制造的影响,这些未来可能用作芯片实验室(LOC)设备。LOC仪器使我们能够在远离固定实验室的地方进行广泛的分析。表征的聚合物种类是用于LOC开发的生物传感器或传感器技术中有前景的候选材料,不仅用于制造这些设备,还作为生物活性材料固定的表面。生物化合物的存在可以提高分析工具的灵敏度和选择性,这在医学诊断中极其重要。所描述的材料具有生物相容性、成本效益高、柔韧性好,是固定特定化合物的优良平台。