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Anti-IgLON5 Disease Responsive to Immunotherapy: A Case Report with an Abnormal MRI.

作者信息

Moreno-Estébanez Ana, Garcia-Ormaechea Milagros, Tijero Beatriz, Fernández-Valle Tamara, Gómez-Esteban Juan Carlos, Berganzo Koldo

机构信息

Neurology Department Cruces University Hospital Plaza Cruces s/n, 48903 Barakaldo Basque Country Spain.

Immunology Department Centre Diagnostic Biomedic (CDB), Hospital Clínic Barcelona Spain.

出版信息

Mov Disord Clin Pract. 2018 Nov 8;5(6):653-656. doi: 10.1002/mdc3.12679. eCollection 2018 Nov-Dec.

DOI:10.1002/mdc3.12679
PMID:30637290
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6277367/
Abstract
摘要

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Anti-IgLON5 Disease Responsive to Immunotherapy: A Case Report with an Abnormal MRI.对免疫疗法有反应的抗IgLON5疾病：一例伴有MRI异常的病例报告
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Epileptic Seizures and Right-Sided Hippocampal Swelling as Presenting Symptoms of Anti-IgLON5 Disease: A Case Report and Systematic Review of the Literature.癫痫发作和右侧海马肿胀作为抗IgLON5病的首发症状：一例报告及文献系统综述
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Sleep Disturbances Associated with Neurological Autoimmunity.与神经自身免疫相关的睡眠障碍。
Neurotherapeutics. 2021 Jan;18(1):181-201. doi: 10.1007/s13311-021-01020-x. Epub 2021 Mar 30.
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Early immunotherapy is highly effective in IgG1/IgG4 positive IgLON5 disease.早期免疫疗法对IgG1/IgG4阳性的IgLON5疾病非常有效。
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Associations between HLA and autoimmune neurological diseases with autoantibodies.HLA与伴有自身抗体的自身免疫性神经疾病之间的关联。
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本文引用的文献

1
IgLON5 disease responsive to immunotherapy.对免疫疗法有反应的IgLON5疾病。
Neurol Neuroimmunol Neuroinflamm. 2017 Aug 7;4(5):e383. doi: 10.1212/NXI.0000000000000383. eCollection 2017 Sep.
2
IgLON5 antibody: Neurological accompaniments and outcomes in 20 patients.IgLON5抗体：20例患者的神经学伴随症状及转归
Neurol Neuroimmunol Neuroinflamm. 2017 Jul 18;4(5):e385. doi: 10.1212/NXI.0000000000000385. eCollection 2017 Sep.
3
Clinical manifestations of the anti-IgLON5 disease.抗IgLON5疾病的临床表现。
Neurology. 2017 May 2;88(18):1736-1743. doi: 10.1212/WNL.0000000000003887. Epub 2017 Apr 5.
4
Chorea and parkinsonism associated with autoantibodies to IgLON5 and responsive to immunotherapy.与IgLON5自身抗体相关且对免疫治疗有反应的舞蹈症和帕金森症。
J Neuroimmunol. 2016 Nov 15;300:9-10. doi: 10.1016/j.jneuroim.2016.09.012. Epub 2016 Sep 24.
5
Neuropathological criteria of anti-IgLON5-related tauopathy.抗IgLON5相关tau蛋白病的神经病理学标准。
Acta Neuropathol. 2016 Oct;132(4):531-43. doi: 10.1007/s00401-016-1591-8. Epub 2016 Jun 29.
6
Metals and Neuronal Metal Binding Proteins Implicated in Alzheimer's Disease.与阿尔茨海默病相关的金属及神经元金属结合蛋白
Oxid Med Cell Longev. 2016;2016:9812178. doi: 10.1155/2016/9812178. Epub 2016 Jan 10.
7
A novel non-rapid-eye movement and rapid-eye-movement parasomnia with sleep breathing disorder associated with antibodies to IgLON5: a case series, characterisation of the antigen, and post-mortem study.一种新型非快速眼动和快速眼动睡眠障碍相关呼吸暂停与 IgLON5 抗体相关：病例系列、抗原特征和尸检研究。
Lancet Neurol. 2014 Jun;13(6):575-86. doi: 10.1016/S1474-4422(14)70051-1. Epub 2014 Apr 3.
8
Pathogenic implications of iron accumulation in multiple sclerosis.铁蓄积在多发性硬化症中的致病意义。
J Neurochem. 2012 Jan;120(1):7-25. doi: 10.1111/j.1471-4159.2011.07536.x. Epub 2011 Nov 11.
9
Single particle analysis of tau oligomer formation induced by metal ions and organic solvents.金属离子和有机溶剂诱导的 tau 低聚物形成的单颗粒分析。
Biochem Biophys Res Commun. 2011 Jul 22;411(1):190-6. doi: 10.1016/j.bbrc.2011.06.135. Epub 2011 Jun 24.
10
Iron (III) induces aggregation of hyperphosphorylated tau and its reduction to iron (II) reverses the aggregation: implications in the formation of neurofibrillary tangles of Alzheimer's disease.三价铁诱导过度磷酸化tau蛋白聚集，而其还原为二价铁可逆转这种聚集：对阿尔茨海默病神经原纤维缠结形成的影响。
J Neurochem. 2002 Sep;82(5):1137-47. doi: 10.1046/j.1471-4159.2002.t01-1-01061.x.