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美沙酮维持治疗药物对美国住院治疗完成和保留的影响。

The effect of medications for opioid use disorder (MOUD) on residential treatment completion and retention in the US.

机构信息

Department of Geography and Urban Studies, Temple University, Philadelphia, PA 19122, United States.

出版信息

Drug Alcohol Depend. 2020 Jul 1;212:108067. doi: 10.1016/j.drugalcdep.2020.108067. Epub 2020 May 15.

Abstract

BACKGROUND

This study examines whether MOUD increases treatment completion and retention in both short-term (ST) and long-term (LT) residential programs using a national dataset.

METHODS

Data were extracted from the 2015-2017 TEDS-D (Treatment Episode Dataset-Discharge) datasets for opioid using adults in ST (n = 87,296) and LT (n = 66,623) residential treatment. Primary outcome variables were treatment completion and retention (ST: length of stay >10 days; LT: >90 days). Logistic regression estimated the effects of MOUD on the probability of treatment completion and retention separately for ST and LT residential treatment, controlling for individual background characteristics.

RESULTS

Only 18% of clients in residential treatment programs had MOUD in their treatment plans. For ST residential treatment, MOUD was associated with a 40% increased likelihood of treatment completion (OR = 1.404) and 34% increased retention (OR = 1.337). For LT residential treatment, MOUD was associated with a 26% reduced likelihood of treatment completion (OR = 0.743) and no significant increase in retention. Post hoc analysis suggests insurance coverage may be influencing outcomes.

CONCLUSIONS

Despite MOUD being a standard of care for OUD, MOUD is particularly under-utilized in residential treatment. Further research should focus on how best to integrate MOUD within short-term residential treatment and to explore the potential viability of MOUD in long-term residential programs. Given the risk of overdose following residential treatment, for at least short-term residential programs, this setting may be advantageous for integrating psychosocial treatments with early MOUD engagement in a structured therapeutic environment as part of a long-term continuum of care recovery program.

摘要

背景

本研究使用全国性数据集,考察美沙酮维持治疗(MOUD)是否会提高短期(ST)和长期(LT)住院治疗项目中的治疗完成率和保留率。

方法

从 2015-2017 年 TEDS-D(治疗期数据集-出院)阿片类药物使用成人 ST(n=87296)和 LT(n=66623)住院治疗数据集中提取数据。主要结局变量为治疗完成率和保留率(ST:住院时间>10 天;LT:>90 天)。逻辑回归分别估计了 MOUD 对 ST 和 LT 住院治疗的治疗完成率和保留率的影响,同时控制了个体背景特征。

结果

只有 18%的住院治疗计划中的患者有 MOUD 治疗计划。对于 ST 住院治疗,MOUD 与治疗完成率增加 40%(OR=1.404)和保留率增加 34%(OR=1.337)相关。对于 LT 住院治疗,MOUD 与治疗完成率降低 26%(OR=0.743)和保留率无显著增加相关。事后分析表明,保险覆盖可能会影响结果。

结论

尽管 MOUD 是 OUD 的标准治疗方法,但 MOUD 在住院治疗中的应用尤其不足。进一步的研究应集中在如何最好地将 MOUD 整合到短期住院治疗中,并探索 MOUD 在长期住院治疗项目中的潜在可行性。鉴于住院治疗后过量用药的风险,对于至少短期住院治疗项目而言,这种环境可能有利于在结构化治疗环境中整合心理社会治疗和早期 MOUD 参与,作为长期康复计划连续性护理的一部分。

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