治疗中的保留和治疗依从性：这些与治疗成功有何关联？使用真实世界数据进行的分析。
Retention in treatment and therapeutic adherence: How are these associated with therapeutic success? An analysis using real-world data.
机构信息
Department of Clinical and Experimental Psychology, University of Huelva, Huelva, Spain.
Research Center on Natural Resources, Health and the Environment, University of Huelva, Huelva, Spain.
出版信息
Int J Methods Psychiatr Res. 2022 Dec;31(4):e1929. doi: 10.1002/mpr.1929. Epub 2022 Jun 28.
INTRODUCTION
Treatment retention and adherence are used as outcomes in numerous randomized clinical trials and observational studies conducted in the addiction field. Although usual criteria are 3/6 months of treatment retention or number of sessions attended, there is not a methodological support for conclusions using these criteria. This study analyzed the usefulness of retention and adherence to predict therapeutic success.
METHODS
Retrospective observational study using real-world data from electronic health records of 11,907 patients in treatment diagnosed with cocaine, alcohol, cannabis and opiate use disorders or harmful use.
RESULTS
Moderate effect size relations were found between the different type of clinical discharge and months in retention (η = 0.12) and proportion of attendance (η = 0.10). No relationship was found with the number of sessions attended. Using cut-off points (i.e., 3 or 6 months in treatment or attending 6 therapy sessions) worsens the ability to predict the type of discharge.
DISCUSSIONS/CONCLUSION: Treatment retention and adherence are indicators moderately related to therapeutic success. Research using these indicators to assess the effectiveness of therapies should complement their results with other clinical indicators and quality of life measures.
简介
在成瘾领域进行的许多随机临床试验和观察性研究中，治疗保留率和治疗依从性被用作结果。尽管通常的标准是保留治疗 3/6 个月或参加的治疗次数，但使用这些标准得出结论并没有方法学支持。本研究分析了保留和依从性预测治疗成功的有用性。
方法
这是一项回顾性观察性研究，使用了来自电子健康记录中 11907 名可卡因、酒精、大麻和阿片类药物使用障碍或有害使用患者治疗的真实世界数据。
结果
发现不同类型的临床出院与保留时间（η=0.12）和出席比例（η=0.10）之间存在中等效应大小关系。与参加的治疗次数没有关系。使用截止点（即治疗 3 或 6 个月或参加 6 次治疗）会降低预测出院类型的能力。
讨论/结论：治疗保留率和治疗依从性是与治疗成功中度相关的指标。使用这些指标评估治疗效果的研究应将其结果与其他临床指标和生活质量测量相结合。
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