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两种活性炭对美国药典模拟肠液和美国药典模拟胃液中苯巴比妥的吸附作用。

Phenobarbital adsorption from simulated intestinal fluid, U.S.P., and simulated gastric fluid, U.S.P., by two activated charcoals.

作者信息

Wurster D E, Burke G M, Berg M J, Veng-Pedersen P, Schottelius D D

机构信息

College of Pharmacy, University of Iowa, Iowa City 52242.

出版信息

Pharm Res. 1988 Mar;5(3):183-6. doi: 10.1023/a:1015969008019.

DOI:10.1023/a:1015969008019
PMID:3244631
Abstract

Adsorption of phenobarbital from simulated intestinal and gastric fluids by two activated charcoals was studied. Adsorption isotherm data were analyzed by the linearized Langmuir equation and by nonlinear least-squares regression employing both Langmuir and Freundlich models. These analyses indicated differences in the capacities of the two charcoals for phenobarbital which could not be completely explained by surface-area considerations.

摘要

研究了两种活性炭对苯巴比妥在模拟肠液和胃液中的吸附情况。采用线性化的朗缪尔方程以及运用朗缪尔模型和弗伦德里希模型的非线性最小二乘法回归对吸附等温线数据进行了分析。这些分析表明，两种活性炭对苯巴比妥的吸附能力存在差异，而仅通过比表面积考量无法完全解释这种差异。

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In vitro adsorption-desorption of fluphenazine dihydrochloride and promethazine hydrochloride by microcrystalline cellulose.微晶纤维素对盐酸氟奋乃静和盐酸异丙嗪的体外吸附-解吸作用
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Comparative absorption, distribution, and excretion of titanium dioxide and zinc oxide nanoparticles after repeated oral administration.重复经口给予后二氧化钛和氧化锌纳米颗粒的吸收、分布和排泄比较。
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Prediction of adsorption from multicomponent solutions by activated carbon using single-solute parameters. Part II--Proposed equation.使用单溶质参数通过活性炭预测多组分溶液中的吸附。第二部分——提出的方程。
AAPS PharmSciTech. 2002;3(3):E23. doi: 10.1208/pt030323.
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Phenobarbital removal characteristics of three brands of activated charcoals: a system analysis approach.三种品牌活性炭对苯巴比妥的去除特性：一种系统分析方法
Pharm Res. 1994 Feb;11(2):318-23. doi: 10.1023/a:1018980029882.
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Model selection for the adsorption of phenobarbital by activated charcoal.
Pharm Res. 1991 Feb;8(2):228-31. doi: 10.1023/a:1015800322286.
9
Surface characterization of activated charcoal by X-ray photoelectron spectroscopy (XPS): correlation with phenobarbital adsorption data.用X射线光电子能谱（XPS）对活性炭进行表面表征：与苯巴比妥吸附数据的相关性
Pharm Res. 1992 Jan;9(1):126-30. doi: 10.1023/a:1018900431661.
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Effect of charcoal and sorbitol-charcoal suspension on the elimination of intravenous phenobarbital.活性炭和山梨醇 - 活性炭混悬液对静脉注射苯巴比妥消除的影响。
Ther Drug Monit. 1987;9(1):41-7. doi: 10.1097/00007691-198703000-00008.