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喂食各种市售钙补充剂或酸奶的衰老雌性大鼠的矿物质代谢

Mineral metabolism of aging female rats fed various commercially available calcium supplements or yogurt.

作者信息

Behling A R, Greger J L

机构信息

Department of Nutritional Sciences, University of Wisconsin, Madison 53706.

出版信息

Pharm Res. 1988 Aug;5(8):501-5. doi: 10.1023/a:1015917307961.

Abstract

The utilization of calcium from commercially available calcium supplements and yogurt and the effects of these calcium supplements on the utilization of other minerals were evaluated. Moderate and high levels (4 and 8 mg Ca/g diet) of calcium from four different sources of dietary calcium (yogurt, calcium phosphate dibasic, calcium magnesium chelate, and oyster shells) were fed to retired female breeder rats. Rats absorbed calcium equally efficiently from all four sources but ingestion of calcium phosphate dibasic tended to cause abnormal accumulation of calcium in kidneys. Ingestion of the calcium magnesium chelate improved calcium retention in bone but depressed the digestibility of the total diet. The elevation of dietary calcium did not affect tissue calcium levels or fecal beta-glucuronidase activity but depressed the apparent absorption of phosphorus, increased kidney phosphorus levels, decreased tibia iron levels, and decreased the digestibility of the total diet.

摘要

对市售钙补充剂和酸奶中钙的利用率以及这些钙补充剂对其他矿物质利用率的影响进行了评估。将来自四种不同膳食钙源(酸奶、磷酸二钙、钙镁螯合物和牡蛎壳)的中等和高水平(4和8毫克钙/克日粮)的钙喂给退休的雌性繁殖大鼠。大鼠从所有四种来源吸收钙的效率相同,但摄入磷酸二钙往往会导致肾脏中钙的异常积累。摄入钙镁螯合物可改善骨骼中的钙保留,但会降低总日粮的消化率。日粮钙的增加不影响组织钙水平或粪便β-葡萄糖醛酸酶活性,但会降低磷的表观吸收率,增加肾脏磷水平,降低胫骨铁水平,并降低总日粮的消化率。

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