Greger J L, Krashoc C L
Department of Nutritional Sciences, University of Wisconsin, Madison.
Drug Nutr Interact. 1988;5(4):387-94.
The effects of commercially available calcium supplements (calcium carbonate, oyster shell, chelated calcium and magnesium, calcium phosphate dibasic) and milk on tissue levels and apparent absorption of calcium, magnesium, phosphorus, iron, zinc, and copper were evaluated with rats that had been made anemic by dietary iron depletion. Hematocrits of anemic rats fed the chelated calcium and magnesium were restored more slowly than rats fed the other calcium sources. The rats fed chelated calcium and magnesium also retained less iron in their livers than rats fed calcium phosphate dibasic, oyster shells, or calcium carbonate and retained less calcium in bone than rats fed milk, oyster shells, or calcium phosphate dibasic. Rats fed calcium phosphate dibasic had on average 40-fold higher levels of calcium in their kidneys than rats fed the other diets. The molar ratio of additional calcium and phosphorus in kidneys of these rats was 3:2.
用因缺铁饮食而致贫血的大鼠，评估市售钙补充剂（碳酸钙、牡蛎壳、螯合钙镁、磷酸氢钙）和牛奶对组织中钙、镁、磷、铁、锌及铜水平以及钙、镁、磷、铁、锌、铜表观吸收率的影响。与喂食其他钙源的大鼠相比，喂食螯合钙镁的贫血大鼠的血细胞比容恢复得更慢。与喂食磷酸氢钙、牡蛎壳或碳酸钙的大鼠相比，喂食螯合钙镁的大鼠肝脏中铁的留存较少；与喂食牛奶、牡蛎壳或磷酸氢钙的大鼠相比，其骨骼中钙的留存较少。喂食磷酸氢钙的大鼠肾脏中的钙水平平均比喂食其他饮食的大鼠高40倍。这些大鼠肾脏中额外的钙与磷的摩尔比为3:2。
