Lundberg U, Holmberg L, Frankenhaeuser M
Department of Psychiatry, Karolinska Institutet, Stockholm, Sweden.
Pharmacol Biochem Behav. 1988 Oct;31(2):287-9. doi: 10.1016/0091-3057(88)90347-4.
Comparisons between catecholamines determined by HPLC (with electrochemical detection) and fluorometry in urine samples from healthy adults and children, respectively, showed high correlations. In agreement with greater specificity for HPLC, mean values were higher for the fluorometric assay. However, it was concluded that fluorometric assays provide as valid and sensitive indices of stress-induced changes in catecholamine excretion in humans as HPLC.
分别对健康成人和儿童尿液样本中通过高效液相色谱法(电化学检测)和荧光法测定的儿茶酚胺进行比较,结果显示二者具有高度相关性。与高效液相色谱法更高的特异性一致,荧光测定法的平均值更高。然而,得出的结论是,荧光测定法与高效液相色谱法一样,可为人类应激诱导的儿茶酚胺排泄变化提供有效且灵敏的指标。