刺山柑抗炎成分的分离与鉴定
Isolation and identification of an anti-inflammatory principle from Capparis spinosa.
作者信息
al-Said M S, Abdelsattar E A, Khalifa S I, el-Feraly F S
机构信息
Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
出版信息
Pharmazie. 1988 Sep;43(9):640-1.
PMID:3244735
Abstract
The homologous polyprenols cappaprenol-12 (1), cappaprenol-13 (2) and cappaprenol-14 (3) with 12, 13 and 14 isoprene units, respectively, could be isolated by preparative HPLC from alcoholic extracts of Capparis spinosa. Testing 2 for its anti-inflammatory activity an inhibition of the carrageenan-induced paw edema in rats of 44 vs. 67% for the standard oxyphenbutazone was found.
摘要
分别含有12、13和14个异戊二烯单元的同源聚戊烯醇卡帕戊烯醇-12（1）、卡帕戊烯醇-13（2）和卡帕戊烯醇-14（3），可以通过制备型高效液相色谱从刺山柑的乙醇提取物中分离得到。对2进行抗炎活性测试时，发现其对大鼠角叉菜胶诱导的爪肿胀的抑制率为44%，而标准品奥昔芬布宗的抑制率为67%。
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