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术前 HbA1c 作为腕管松解术的标准化方案的效用:临床结局的回顾性研究。

The Utility of Preoperative HbA1c as a Standardized Protocol in Elective Carpal Tunnel Release: A Retrospective Review of Clinical Outcomes.

机构信息

Virginia Tech Carilion School of Medicine, Roanoke, USA.

Virginia Tech, Blacksburg, USA.

出版信息

Hand (N Y). 2022 Mar;17(2):224-230. doi: 10.1177/1558944720919181. Epub 2020 May 23.

DOI:10.1177/1558944720919181
PMID:32447994
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8984731/
Abstract

In an effort to reduce surgical complications, some institutions have implemented universal hemoglobin A1c (HbA1c) screening for all preoperative patients. However, the value of HbA1c screening for predicting clinically meaningful complications after elective carpal tunnel release (CTR) remains unclear. The purpose of this study was to investigate the clinically meaningful predicative value of HbA1c screening on postoperative complications following elective CTR. A retrospective cohort study of 790 patients who underwent CTR was performed. All patients had an HbA1c screening performed, regardless of whether they underwent the diagnosis for diabetes or not. Primary outcomes were overall complication rate, rates of major complications (readmission or reoperation), and rates of minor complications (surgical site infection and wound dehiscence). Patients were stratified into 3 groups based on HbA1c: HbA1c <7, HbA1c 7-8, and HbA1c >8. The overall complication rate for all groups was 4.8%. Rates of major complications were 0.4% for readmission and 0.1% for reoperation. For minor complications, the odds ratio (OR) for the HbA1c 7-8 group was 0.6 (95% confidence interval [CI], 0.14-1.77), and for the HbA1c >8 group, the OR was 1.6 (95% CI, 0.66-3.60). All minor complications resolved with outpatient treatment. There were no statistically significant differences between the groups for any comparisons. Elective CTR has a low complication rate. Routine preoperative screening of HbA1c is of little value in predicting clinically meaningful complications.

摘要

为了降低手术并发症的发生率,一些机构已经对所有术前患者实施了普遍的血红蛋白 A1c(HbA1c)筛查。然而,HbA1c 筛查对预测择期腕管松解术(CTR)后临床有意义的并发症的价值仍不清楚。本研究旨在探讨 HbA1c 筛查对择期 CTR 后术后并发症的临床有意义的预测价值。

对 790 例行 CTR 的患者进行了回顾性队列研究。所有患者均进行了 HbA1c 筛查,无论他们是否因糖尿病而进行了诊断。主要结局是总体并发症发生率、主要并发症(再入院或再次手术)发生率和次要并发症(手术部位感染和伤口裂开)发生率。根据 HbA1c 将患者分为 3 组:HbA1c<7、HbA1c 7-8 和 HbA1c>8。所有组的总体并发症发生率为 4.8%。再入院率的主要并发症发生率为 0.4%,再次手术率为 0.1%。对于次要并发症,HbA1c 7-8 组的比值比(OR)为 0.6(95%置信区间[CI],0.14-1.77),HbA1c>8 组的 OR 为 1.6(95%CI,0.66-3.60)。所有的次要并发症都通过门诊治疗解决。各组之间的任何比较均无统计学差异。

择期 CTR 的并发症发生率较低。术前常规筛查 HbA1c 对预测有临床意义的并发症价值不大。

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