Chang S C, Chang K T, Keng Y F, Lan C F, Hsiao H C, Hsen S H, Wei Y H
Department of Biochemistry, National Yang-Ming Medical College, Taipei, Taiwan, Republic of China.
Proc Natl Sci Counc Repub China B. 1988 Jul;12(3):129-39.
The mutagenic activity of dichloromethane extracts of 147 air particulate samples collected from 8 stations during December 1986-June 1987 in Taipei city was consistently higher in S. typhimurium strain TA 98 than in strain TA 100 in the presence of S9 mixture. Among the 8 stations, Nan Kang Police Station, Fu Hsing Elementary School, and Chung Hsing University which were located in the industrial district, downtown area, and heavy traffic zone, respectively, had significantly higher levels of PAHs than the other stations. In contrast, the levels of PAHs were much lower in the suburban station, near Pei Tou Elementary School. However, PAH contents of the air particulate samples collected from these stations did not show good correlation with their mutagenicity. The air particulates collected at some stations on Sunday when the traffic changed from heavy to light showed lower mutagenicity and PAH contents as compared with the other weekdays at the same stations. On the contrary, the samples collected at Pei Tou station in a suburban area where the traffic changed from light to heavy on Sunday showed higher mutagenicity and PAH contents. The monthly average of PAHs of air particulate samples collected over a 7-month period from 8 stations in Taipei city was lower than the average in 1980. Moreover, when compared with other countries, such as U.S.A., the Netherlands, West Germany, Italy, Norway, and Japan, the levels of PAHs and mutagenicity of air particulate matters in Taipei city were similar or slightly lower. The mutagenicity and contents of PAHs of air particulates collected from burnt ABS were significantly higher than those of burnt PVC. One sample PT-6-3 was collected while a nearby garbage collection area was on fire. The mutagenicity of that sample increased 3 to 16 fold and contained an 11 to 33 times higher content of the six PAHs (BaP, BeP, BbF, BaA, Chr, and DbA) as compared with the other samples collected at the same location at a different time. The higher mutagenicity and PAH contents of that sample might be due to the pollution of the air from combustion of the garbage containing products made of ABS.
1986年12月至1987年6月期间，从台北市8个监测站采集的147份空气颗粒物样本的二氯甲烷提取物，在加入S9混合物的情况下，对鼠伤寒沙门氏菌TA 98菌株的致突变活性始终高于TA 100菌株。在这8个监测站中，分别位于工业区、市中心区和交通繁忙区的南港派出所、复兴小学和中兴大学的多环芳烃水平显著高于其他监测站。相比之下，北投小学附近的郊区监测站的多环芳烃水平要低得多。然而，从这些监测站采集的空气颗粒物样本中的多环芳烃含量与其致突变性之间没有显示出良好的相关性。在周日交通从繁忙变为清淡时，一些监测站采集的空气颗粒物的致突变性和多环芳烃含量与同一监测站的其他工作日相比有所降低。相反，在周日交通从清淡变为繁忙的郊区北投监测站采集的样本显示出更高的致突变性和多环芳烃含量。从台北市8个监测站在7个月期间采集的空气颗粒物样本的多环芳烃月平均值低于1980年的平均值。此外，与美国、荷兰、西德、意大利、挪威和日本等其他国家相比，台北市空气颗粒物中的多环芳烃水平和致突变性相似或略低。从燃烧的ABS中采集的空气颗粒物的致突变性和多环芳烃含量明显高于燃烧的PVC。一个样本PT - 6 - 3是在附近一个垃圾收集区着火时采集的。与在同一地点不同时间采集的其他样本相比，该样本的致突变性增加了3至16倍，六种多环芳烃（苯并[a]芘、苯并[e]芘、苯并[b]荧蒽、苯并[a]蒽、䓛和二苯并[a,h]蒽）的含量高出11至33倍。该样本较高的致突变性和多环芳烃含量可能是由于含有ABS制成的产品的垃圾燃烧对空气造成的污染。
