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多学科网络治疗心原性休克患者的初步结果。

Initial outcomes of a multidisciplinary network for the care of patients with cardiogenic shock.

机构信息

Servicio de Cardiología, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, Spain.

Servicio de Anestesia y Reanimación, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, Spain.

出版信息

Rev Esp Cardiol (Engl Ed). 2021 Jan;74(1):33-43. doi: 10.1016/j.rec.2020.03.010. Epub 2020 May 21.

Abstract

INTRODUCTION AND OBJECTIVES

Mortality remains high in cardiogenic shock (CS), especially in refractory CS involving the use of mechanical circulatory support (MCS) devices. The aim of this study was to analyze the results of a care program for patients in CS after the creation of a multidisciplinary team in our center and a regional network of hospitals in our area.

METHODS

Observational and retrospective study of patients attended in this program from September 2014 to January 2019. We included patients in refractory CS who required MCS and those who, because of their age and absence of comorbidities, were candidates for advanced therapies. The primary endpoint was survival to discharge.

RESULTS

A total of 130 patients were included (69 local and 61 transferred patients). The mean age was 52±15 years (72% men). The most frequent causes of CS were acute decompensated heart failure (29%), acute myocardial infarction (26%), and postcardiotomy CS (25%). MCS was used in 105 patients (81%), mostly extracorporeal membrane oxygenation (58%). Survival to discharge was 57% (74 of 130 patients). The most frequent destinations were myocardial recovery and heart transplant. Independent predictors of in-hospital mortality were SAPS II score, lactate level, acute myocardial infarction etiology, and vasoactive-inotropic score.

CONCLUSIONS

The creation of multidisciplinary teams for patients with mainly refractory CS and a regional network is feasible and allows survival to discharge in more than a half of attended patients with CS.

摘要

引言和目的

心源性休克(CS)的死亡率仍然很高,尤其是在涉及使用机械循环支持(MCS)装置的难治性 CS 中。本研究的目的是分析在我们中心创建多学科团队和我们地区的医院区域网络后,CS 患者护理计划的结果。

方法

对 2014 年 9 月至 2019 年 1 月期间参加该计划的患者进行观察性和回顾性研究。我们纳入了需要 MCS 的难治性 CS 患者,以及因年龄和无合并症而适合先进治疗的患者。主要终点是出院时的存活率。

结果

共纳入 130 例患者(69 例本地患者和 61 例转院患者)。平均年龄为 52±15 岁(72%为男性)。CS 的最常见原因是急性失代偿性心力衰竭(29%)、急性心肌梗死(26%)和心脏手术后 CS(25%)。105 例患者(81%)使用了 MCS,主要是体外膜氧合(58%)。出院时的存活率为 57%(130 例患者中有 74 例)。最常见的去向是心肌恢复和心脏移植。住院死亡率的独立预测因素是 SAPS II 评分、乳酸水平、急性心肌梗死病因和血管活性-正性肌力评分。

结论

为主要为难治性 CS 患者创建多学科团队和区域网络是可行的,可使超过一半的 CS 患者出院时存活。

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