Department of Urology, Zealand University Hospital, Roskilde, Denmark.
Section of Nursing, Aarhus University, Emdrup, Denmark.
Scand J Urol. 2020 Jun;54(3):253-257. doi: 10.1080/21681805.2020.1769181. Epub 2020 May 25.
This paper aims to estimate the incidence of post-obstructive diuresis (POD) among patients with urinary retention, explore possible underlying causes and identify patients who need hospitalization. This retrospective study includes patients admitted for urinary retention in Zealand University Hospital, Denmark. We collected demographic characteristics, health information and laboratory results from patients' charts and analyzed data statistically. We assessed 64 patients, and POD occurred in 29.7%. A significant correlation was observed between POD and residual urine, serum creatinine, serum urea and systolic and diastolic blood pressure. We identified increased residual urine volume as an independent predictor of POD by OR 1.21 (95% CI: 1.06-1.40), = 0.006 per 100 mL and creatinine of >120 umol/L is an independent predictor of POD by OR 7.17 (95% CI; 1.63-31.37), = 0.009. Patients with residual urine at the time of diagnosis of more than 1150 ml will suffer POD with a probability of area under curve (AUC) 0.874 ( < 0.001) with 84% sensitivity and 78% specificity. Patients with creatinine >120 umol/L will suffer POD with a probability of AUC 0.774 ( < 0.001) with 68% sensitivity and 82% specificity. In this small retrospective study residual urine of more than 1150 mL and elevated creatinine are independent predictors of POD in patients with urinary retention. However, larger prospective studies are needed to confirm these findings.
本文旨在估计尿潴留患者中梗阻后利尿(POD)的发生率,探讨可能的潜在原因,并确定需要住院的患者。这项回顾性研究包括丹麦 Zealand 大学医院因尿潴留入院的患者。我们从患者的图表中收集了人口统计学特征、健康信息和实验室结果,并对数据进行了统计学分析。我们评估了 64 名患者,其中 29.7%发生了 POD。POD 与残余尿量、血清肌酐、血清尿素、收缩压和舒张压之间存在显著相关性。我们发现,残余尿量增加是 POD 的独立预测因子,OR 为 1.21(95%CI:1.06-1.40),每增加 100ml = 0.006,肌酐>120 umol/L 是 POD 的独立预测因子,OR 为 7.17(95%CI;1.63-31.37), = 0.009。诊断时残余尿量超过 1150ml 的患者发生 POD 的概率为 AUC 0.874( < 0.001),灵敏度为 84%,特异性为 78%。肌酐>120 umol/L 的患者发生 POD 的概率为 AUC 0.774( < 0.001),灵敏度为 68%,特异性为 82%。在这项小型回顾性研究中,残余尿量>1150ml 和肌酐升高是尿潴留患者 POD 的独立预测因子。然而,需要更大的前瞻性研究来证实这些发现。