Lim Yi Guang Jerome, Low Hui Ying Jessalyn, Loo Say Chye Joachim
School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore, 639798, Singapore.
Singapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University, 60 Nanyang Drive, Singapore, 637551, Singapore.
Macromol Rapid Commun. 2020 Nov;41(21):e2000140. doi: 10.1002/marc.202000140. Epub 2020 May 25.
Polymeric Janus particles can be exploited for a myriad of applications. Through the understanding of interfacial tensions, theragnostic agents such as drugs or nanomaterials can be successfully encapsulated into Janus particles without losing their anisotropic structure. In this work, it is reported that how Janus superstructures, as a further extension of the Janus morphology, can be obtained by blending other synthesis parameters into the solvent emulsion process, while adhering to the requirements of the Harkin's spreading coefficient (HSC) theory. Designing such unique structures for drug delivery can provide a broader range of possibilities and applications beyond conventional Janus particles.
聚合物双面粒子可用于众多应用。通过对界面张力的理解，诸如药物或纳米材料等诊疗剂可以成功地封装到双面粒子中而不丧失其各向异性结构。在这项工作中，据报道，作为双面形态的进一步延伸，双面超结构如何通过将其他合成参数融入溶剂乳液法来获得，同时遵循哈金斯铺展系数（HSC）理论的要求。为药物递送设计这样独特的结构可以提供超越传统双面粒子的更广泛的可能性和应用。
