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牛的呼吸细菌微生物组:从发育到调节以增强呼吸健康。

Respiratory Bacterial Microbiota in Cattle: From Development to Modulation to Enhance Respiratory Health.

机构信息

Ceva Santé Animale, 10 Avenue de la Ballastière, Libourne 33500, France.

Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.

出版信息

Vet Clin North Am Food Anim Pract. 2020 Jul;36(2):297-320. doi: 10.1016/j.cvfa.2020.03.001.

DOI:10.1016/j.cvfa.2020.03.001
PMID:32451027
Abstract

The respiratory tract of cattle is colonized by complex bacterial ecosystems also known as bacterial microbiotas. These microbiotas evolve over time and are shaped by numerous factors, including maternal vaginal microbiota, environment, age, diet, parenteral antimicrobials, and stressful events. The resulting microbiota can be diverse and enriched with known beneficial bacteria that can provide colonization resistance against bacterial pathogens or, on the contrary, with opportunistic pathogens that can predispose cattle to respiratory disease. The respiratory microbiota can be modulated by nonantimicrobial approaches to promote health, creating new potential strategies for prevention and treatment of bovine respiratory disease.

摘要

牛的呼吸道被复杂的细菌生态系统定植,这些生态系统也被称为细菌微生物群。这些微生物群随着时间的推移而演变,并受到许多因素的影响,包括母体阴道微生物群、环境、年龄、饮食、全身抗菌药物和应激事件。由此产生的微生物群可以是多样的,并富含已知的有益细菌,这些细菌可以提供对细菌病原体的定植抵抗,或者相反,富含机会性病原体,使牛易患呼吸道疾病。呼吸道微生物群可以通过非抗菌方法进行调节,以促进健康,为预防和治疗牛呼吸道疾病创造新的潜在策略。

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