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用 38 号针头向视网膜下注射平衡盐溶液清除糖尿病患者的黄斑硬性渗出物。

Removal of foveal hard exudates by subretinal balanced salt solution injection using 38-gauge needle in diabetic patients.

机构信息

Kami-iida Daiichi General Hospital, 2-70 Kamiiida Kita-machi, Nagoya, Aichi, 462-0802, Japan.

Shinjo Ophthalmologic Institute, Miyazaki, Japan.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2020 Sep;258(9):1893-1899. doi: 10.1007/s00417-020-04756-y. Epub 2020 May 25.

Abstract

PURPOSE

To examine the anatomic and visual outcomes after removal of foveal hard exudates through a macular hole created by subretinal balanced salt solution (BSS) injection.

METHODS

This was a retrospective, consecutive, case series. Six patients (7 eyes) underwent vitrectomy with removal of foveal hard exudates. All patients were women and the mean age was 65 years (range from 55 to 71). All patients had a history of panretinal photocoagulation. Previous treatments included intravitreal anti-vascular endothelial growth factor injection in one eye and vitrectomy in both eyes of one patient. The geometric mean preoperative decimal visual acuity was 0.11 (range from 0.08 to 0.3). The mean postoperative follow-up period was 12 months (range from 6 to 19). The status of lens was two phakic and five pseudophakic. Surgical procedures included simultaneous cataract surgery if phakic, creation of posterior vitreous detachment if not present, internal limiting membrane (ILM) peeling and a gas or air tamponade. Manual subretinal BSS injection using 38-gauge needle was performed at ILM-peeled area. Removal of foveal hard exudates was conducted by the water flow through the macular hole created during subretinal BSS injection.

RESULTS

Foveal hard exudates decreased in all cases early after surgery. The geometric mean final decimal visual acuity was 0.31 (range from 0.1 to 0.9). Visual acuity improved more than 0.2 LogMAR units in six eyes and unchanged in one eye. There was no severe complication and recurrence of macular edema.

CONCLUSION

This procedure may be effective for foveal hard exudates in diabetic patients.

摘要

目的

通过视网膜下平衡盐溶液(BSS)注射形成的黄斑裂孔,观察去除黄斑中心凹硬性渗出物的解剖和视力结果。

方法

这是一项回顾性、连续性病例系列研究。6 名患者(7 只眼)接受了玻璃体切除术,以去除黄斑中心凹硬性渗出物。所有患者均为女性,平均年龄为 65 岁(55-71 岁)。所有患者均有全视网膜光凝病史。既往治疗包括 1 只眼玻璃体内抗血管内皮生长因子注射和 1 例患者双眼玻璃体切除术。术前十进制最佳矫正视力的几何均数为 0.11(0.08-0.3)。平均术后随访时间为 12 个月(6-19 个月)。晶状体状态为 2 例为晶状体透明,5 例为人工晶状体眼。手术程序包括如果晶状体透明则同时行白内障手术,如果玻璃体后脱离不存在则行后玻璃体脱离,如果不存在内界膜(ILM)剥除和气体或空气填充。在 ILM 剥除区域使用 38 号针头进行手动视网膜下 BSS 注射。通过黄斑裂孔中的水流去除黄斑中心凹硬性渗出物,该黄斑裂孔是在视网膜下 BSS 注射过程中形成的。

结果

所有病例术后早期黄斑中心凹硬性渗出物均减少。最终十进制最佳矫正视力的几何均数为 0.31(0.1-0.9)。6 只眼的视力提高超过 0.2 LogMAR 单位,1 只眼的视力不变。无严重并发症和黄斑水肿复发。

结论

对于糖尿病患者的黄斑中心凹硬性渗出物,该方法可能有效。

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