Kumagai Kazuyuki, Furukawa Mariko, Suetsugu Tetsuyuki, Ogino Nobuchika
Department of Ophthalmology, Kami-iida Daiichi General Hospital.
Department of Ophthalmology, Nishigaki Eye Clinic, Aichi, Japan.
Clin Ophthalmol. 2017 Apr 4;11:605-611. doi: 10.2147/OPTH.S134909. eCollection 2017.
To report the findings in three cases in which the average foveal thickness was increased after a thin epiretinal membrane (ERM) was removed by vitrectomy with internal limiting membrane (ILM) peeling.
The foveal contour was normal preoperatively in all eyes. All cases underwent successful phacovitrectomy with ILM peeling for a thin ERM. The optical coherence tomography (OCT) images were examined before and after the surgery. The changes in the average foveal (1 mm) thickness and the foveal areas within 500 μm from the foveal center were measured. The postoperative changes in the inner and outer retinal areas determined from the cross-sectional OCT images were analyzed.
The average foveal thickness and the inner and outer foveal areas increased significantly after the surgery in each of the three cases. The percentage increase in the average foveal thickness relative to the baseline thickness was 26% in Case 1, 29% in Case 2, and 31% in Case 3. The percentage increase in the foveal inner retinal area was 71% in Case 1, 113% in Case 2, and 110% in Case 3, and the percentage increase in foveal outer retinal area was 8% in Case 1, 13% in Case 2, and 18% in Case 3.
The increase in the average foveal thickness and the inner and outer foveal areas suggests that a centripetal movement of the inner and outer retinal layers toward the foveal center probably occurred due to the ILM peeling.
报告三例通过玻璃体切除术联合内界膜（ILM）剥除术去除薄的视网膜前膜（ERM）后，中央凹平均厚度增加的病例的研究结果。
所有患眼术前中央凹轮廓均正常。所有病例均成功进行了玻璃体切除联合ILM剥除术以治疗薄的ERM。在手术前后检查光学相干断层扫描（OCT）图像。测量中央凹平均（1毫米）厚度以及距中央凹中心500微米范围内的中央凹面积的变化。分析从横断面OCT图像确定的视网膜内、外区域的术后变化。
在这三例病例中，术后中央凹平均厚度以及中央凹内、外区域均显著增加。病例1中，中央凹平均厚度相对于基线厚度的增加百分比为26%，病例2为29%，病例3为31%。病例1中中央凹视网膜内区域的增加百分比为71%，病例2为113%，病例3为110%；病例1中中央凹视网膜外区域的增加百分比为8%，病例2为13%，病例3为18%。
中央凹平均厚度以及中央凹内、外区域的增加表明，由于ILM剥除，视网膜内、外层可能向中央凹中心发生了向心运动。
