From the Division of PET Imaging, Shiga Medical Center Research Institute.
Departments of Thoracic Surgery.
Clin Nucl Med. 2020 Aug;45(8):628-631. doi: 10.1097/RLU.0000000000003078.
Brown adipose tissue (BAT), which produces energy and is known to play a role as a hibernating gland, is sometimes visualized on F-FDG PET in children or in slender young adults in a cold environment. Because BAT is activated by catecholamines, FDG uptake in BAT is also observed in patients with pheochromocytoma or paraganglioma. We present the case of an elderly woman with remarkable FDG uptake in BAT. Activation of BAT by a β3-adrenergic receptor agonist (mirabegron) prescribed for overactive bladder was suspected as the cause of the marked visualization of BAT in this patient.
棕色脂肪组织（BAT）是一种产热组织，已知其在冬眠腺体中发挥作用，在儿童或在寒冷环境中的苗条年轻成年人中，有时可以通过 F-FDG PET 观察到。由于 BAT 被儿茶酚胺激活，因此在患有嗜铬细胞瘤或副神经节瘤的患者中也可以观察到 FDG 在 BAT 中的摄取。我们报告了一例老年女性 BAT 中出现明显 FDG 摄取的病例。怀疑该患者 BAT 明显显像是由于开给她治疗膀胱过度活动症的β3 肾上腺素能受体激动剂（米拉贝隆）激活了 BAT。
